Biomarkers of liver fibrosis: prospective comparison of multimodal magnetic resonance, serum algorithms and transient elastography

MF Forsgren, P Nasr, M Karlsson… - Scandinavian Journal …, 2020 - Taylor & Francis
Background and aims Accurate biomarkers for quantifying liver fibrosis are important for
clinical practice and trial end-points. We compared the diagnostic performance of magnetic …

[HTML][HTML] Hybrid modelling for stroke care: Review and suggestions of new approaches for risk assessment and simulation of scenarios

T Herrgårdh, VI Madai, JD Kelleher, R Magnusson… - NeuroImage: Clinical, 2021 - Elsevier
Stroke is an example of a complex and multi-factorial disease involving multiple organs,
timescales, and disease mechanisms. To deal with this complexity, and to realize Precision …

Comparison of liver scintigraphy and the liver-spleen contrast in Gd-EOB-DTPA-enhanced MRI on liver function tests

H Mori, H Machimura, A Iwaya, M Baba, K Furuya - Scientific Reports, 2021 - nature.com
The liver-spleen contrast (LSC) using hepatobiliary-phase images could replace the
receptor index (LHL15) in liver scintigraphy; however, few comparative studies exist. This …

Liver Intrinsic Function Evaluation (LIFE): Multi-parametric Liver Function Profiles of Patients Undergoing Hepatectomy

C Simonsson, WC Bartholomä, AL Larsson, M Karlsson… - medRxiv, 2024 - medrxiv.org
Abstract Background & Aims For a range of liver malignancies, the only curative treatment
option may be hepatectomy, which may have fatal complications. Therefore, an unbiased …

Mathematical models for biomarker calculation of drug-induced liver injury in humans and experimental models based on gadoxetate enhanced magnetic resonance …

M Karlsson, C Simonsson, N Dahlström, G Cedersund… - Plos one, 2023 - journals.plos.org
Background Drug induced liver injury (DILI) is a major concern when developing new drugs.
A promising biomarker for DILI is the hepatic uptake rate of the contrast agent gadoxetate …

[图书][B] Non-Invasive Characterization of Liver Disease: By Multimodal Quantitative Magnetic Resonance

M Karlsson - 2019 - books.google.com
There is a large and unmet need for diagnostic tool that can be used to characterize chronic
liver diseases (CLD). In the earlier stages of CLD, much of the diagnostics involves …

Mathematical modeling of neurovascular coupling

S Sten - 2020 - diva-portal.org
The brain is critically dependent on the continuous supply of oxygen and glucose, which is
carried and delivered by blood. When a brain region is activated, metabolism of these …

In silico liver resection to estimate global and regional hepatobiliary function

C Simonsson, WC Bartholomä, AL Larsson, M Karlsson… - archive.ismrm.org
In some cases, treatment of severe liver diseases requires resective surgery. This brings
serious complications if the remnant tissue fails to match the requirement of liver function …

Applications of Quantitative Perfusion and Permeability in the Liver

M Ronot, F Joly, BE Van Beers - Advances in Magnetic Resonance …, 2020 - Elsevier
Because of the unique hepatic structure, quantification of perfusion is more challenging in
the liver than in other organs. The liver is a large, mobile organ that moves significantly …

[PDF][PDF] Non-Invasive Characterization of Liver Disease

M Karlsson - 2019 - researchgate.net
There is a large and unmet need for diagnostic tool that can be used to characterize chronic
liver diseases (CLD). In the earlier stages of CLD, much of the diagnostics involves …