An emerging body of literature demonstrates differences in the gut microbiome (GMB) of
patients with major depressive disorder (MDD) compared to healthy controls (HC), as well …

The emergence of the coronavirus disease 2019 pandemic has dramatically increased the
global prevalence of depression. Unfortunately, antidepressant drugs benefit only a small …

The gut microbiota is critical for maintaining human health and the immunological system.
Several neuroscientific studies have shown the significance of microbiota in developing …

The α7 subtype of the nicotinic acetylcholine receptor (α7 nAChR: coded by Chrna7) is
known to regulate the cholinergic ascending anti-inflammatory pathway. We previously …

Background: The gut microbiota impacts on central nervous system (CNS) function via the
microbiota–gut–brain axis. Thus, therapeutics targeting the gut microbiota such as probiotics …

Studies investigating gut microbiota composition in depressive disorder have yielded mixed
results. The aim of our study was to compare gut microbiome between people with …

Disturbed gut microbiota is a potential factor in the pathogenesis of major depressive
disorder (MDD), yet whether gut microbiota dysbiosis is associated with the severity of MDD …

Depressive disorders can affect up to 350 million people worldwide, and in developed
countries, the percentage of patients with depressive disorders may be as high as 10 …

Major depressive disorder (MDD) is currently the main cause of disability worldwide, but its
pathophysiology remains largely unknown, especially given its high heterogeneity in terms …

The prevalence of anxiety and depression soared following the COVID-19 pandemic. To
effectively treat these conditions, a comprehensive understanding of all etiological factors is …