Abstract Human kallikreins 5 and 7 (KLK5 and KLK7) exhibit trypsin-and chymotrypsin-like
activities and are involved in pathologies related to skin desquamation process. A series of …

COVID-19 is a multisystemic disease caused by the SARS-CoV-2 airborne virus, a member
of the Coronaviridae family. It has a positive sense single-stranded RNA genome and …

A highly regio-and stereoselective synthesis of novel β, γ-disubstituted γ-lactams with either
an anti or syn relative configuration was developed from readily available epoxide and …

Copper catalyzed oxidative cross-coupling of aromatic amines with 2-pyrrolidinone: a facile
synthesis of N-aryl-γ-amino-γ-lactams - ScienceDirect Skip to main contentSkip to article …

This review presents a systematic survey of the literature (through the end of 2014) for de
novo syntheses of 3-pyrrolin-2-ones from acyclic precursors or via transformation of other …

A new synthetic route towards chiral 3, 5‐disubstituted pyrrol‐2‐ones by starting from amino
acids has been developed. The sequence features the conversion of amino acids into their …

A general route which provides direct access to pyroglutamates from tetramates, making use
of Suzuki coupling on an enol mesylate, followed by reduction, is reported. This work permits …

Conjugate addition of benzylamine to chiral methyl cis-3-aziridin-2-yl-acrylates was
successfully proceeded to yield 3-aziridin-2-yl-3-benzylaminopropionates in high yield with …

The synthesis of 1-alkyl (aryl)-5-(3, 3, 3-trihalo-2-oxopropylidene)-1H-pyrrol-2 (5H)-ones 5,
6a–d from 1-alkyl (aryl)-4-bromo-5-(3, 3, 3-trihalo-2-oxopropylidene)-1H-pyrrolidin-2-ones 3 …

Access to β,γ-diamino acids. Application to the synthesis of 3-deoxyaminostatine - Organic
& Biomolecular Chemistry (RSC Publishing) DOI:10.1039/C0OB00370K Royal Society of …