Solvatochromic dyes have emerged as a new class of fluorescent probes in the field of lipid
membranes due to their ability to identify the lipid organization of biomembranes in live cells …

The structural diversity of different lipid species within the membrane defines its biophysical
properties such as membrane fluidity, phase transition, curvature, charge distribution, and …

The glucagon receptor family are typical class B1 G protein-coupled receptors (GPCRs) with
important roles in metabolism, including the control of pancreas, brain, and liver function. As …

Protozoan parasites use cAMP signaling to precisely regulate the place and time of
developmental differentiation, yet it is unclear how this signaling is initiated. Encystation of …

Simvastatin belongs to the statin family of cholesterol lowering drugs which act as
competitive inhibitors of HMG-CoA reductase, the rate-determining enzyme in cholesterol …

N‑Acylserinols (NASOHs) exhibit anti-cancer activity by elevating ceramide levels, and/or by
activating proapoptotic effectors. In the present work we investigated the thermotropic phase …

The molecular mechanism underlying the action of local anesthetics remains elusive.
Phenylethanol (PEtOH) is an ingredient of essential oils with a rose-like odor and has been …

Evodiamine has been documented to possess activities in numerous cancer cells. Our
preliminary study showed that A549 cells were insensitive to evodiamine. In this paper …

The composition of neuronal membranes is unique with diverse lipid composition due to
evolutionary requirement. The organization and dynamics of neuronal membranes are …

The fundamental mechanism behind the action of local anesthetics is still not clearly
understood. Phenylethanol (PEtOH) is a constituent of essential oils with a pleasant odor …