Metal complexes have been widely used for applications in the chemical and physical
sciences due to their unique electronic and stereochemical properties. For decades the use …

Our desire to understand how the individual molecules that make up cells organize, interact,
and communicate to form living systems has led to the burgeoning field of chemical biology …

This review provides an introduction into the fascinating area of organometallic anticancer
compounds. Although the subject dates back many years, it has witnessed considerable …

The study of metal complexes for the treatment of cancer diseases has resulted in the
identification of some unique properties of ruthenium-based compounds. Among these …

Neurodegenerative disease (NDD), including Alzheimer's disease, Parkinson's disease, and
amyotrophic lateral sclerosis, are characterized by the progressive loss of neurons which …

Interest in the medicinal properties of ruthenium (II)–arene compounds has grown rapidly
over the last decade. In this account we describe the origins of the field and subsequently …

The field of medicinal inorganic chemistry has evolved with three conceptual aims: the
introduction of metal ions to the biological system, manipulation and redistribution of metal …

Altering biological processes with small synthetic molecules is a general approach for the
design of drugs and molecular probes. Medicinal chemistry and chemical biology are …

Unique properties of metal complexes, such as structural diversity, adjustable ligand
exchange kinetics, fine-tuned redox activities, and distinct spectroscopic signatures, make …

Unexpected side effects and problems experienced in clinical trials have created a difficult
environment for those developing new pharmaceuticals and, as a consequence, the number …