Background Helicobacter pylori is a gastrointestinal pathogen that infects around half of the
world's population. H. pylori infection is the most severe known risk factor for gastric cancer …

Non-invasive diagnostic biomarkers may contribute to an early identification of gastric
cancer (GC) and improve the clinical management. Unfortunately, no sensitive and specific …

Non-coding RNAs (ncRNAs) have recently become increasingly important in the study of
cellular metabolism and regulation such as development, proliferation, differentiation and …

Long non-coding RNAs (lncRNAs) were shown to play critical roles in cancer biology. We
investigated whether H. pylori infection could promote gastric cancer by regulating lncRNAs …

Gastric cancer is a common heterogeneous malignancy that is pathologically characterized
by the development of chronic atrophic gastritis and dysplasia of the epithelium. The …

Colorectal cancer (CRC) is one of the most common cancers worldwide with high mortality
rates. MicroRNAs (miRNAs) have an established role in the development of different …

Abstract Background Micro-RNAs are implicated in various physiological and pathologic
processes. In this study, we tested whether Micro-RNA gene variants of host-genome affect …

Background: Accumulating evidence suggests that functional dysregulations of miRNAs,
especially miR-196a-2 and miR-149, in cancers could be attributed to polymorphisms in …

Gastric cancer (GC) remains one of the most common causes of mortality worldwide.
Intestinal metaplasia (IM) is one of the preneoplastic gastric lesions and is considered an …

Aim: Single nucleotide polymorphisms in miRNA-coding region may be involved in the
development or progression of gastric cancer (GC). Materials & methods: Six SNPs (miR …