[HTML][HTML] Reviving the interest in the versatile drug nystatin: A multitude of strategies to increase its potential as an effective and safe antifungal agent

F Sousa, C Nascimento, D Ferreira, S Reis… - Advanced Drug Delivery …, 2023 - Elsevier
Nystatin is an antifungal molecule with a remarkable yet squandered versatility. In this
review, its mechanism of action is explored, along with its extensive action spectrum and …

New strategies for local treatment of vaginal infections

R Palmeira-de-Oliveira, A Palmeira-de-Oliveira… - Advanced drug delivery …, 2015 - Elsevier
Vaginal infections are extremely prevalent, particularly among women of reproductive age.
Although they do not result in high mortality rates, these infections are associated with high …

Recent advances in polymer-based vaginal drug delivery systems

T Osmałek, A Froelich, B Jadach, A Tatarek… - Pharmaceutics, 2021 - mdpi.com
The vagina has been considered a potential drug administration route for centuries. Most of
the currently marketed and investigated vaginal formulations are composed with the use of …

Promising drug delivery approaches to treat microbial infections in the vagina: A recent update

M Pandey, H Choudhury, A Abdul-Aziz, SK Bhattamisra… - Polymers, 2020 - mdpi.com
An optimal host–microbiota interaction in the human vagina governs the reproductive health
status of a woman. The marked depletion in the beneficial Lactobacillus sp. increases the …

Augmented control of drug-resistant Candida spp. via fluconazole loading into fungal chitosan nanoparticles

HA El Rabey, FM Almutairi, AI Alalawy… - International Journal of …, 2019 - Elsevier
Fungal chitosan (ACT) extraction from Amylomyces rouxii, its transforming into nano-form,
loading with fluconazole (Flu) and evaluation of synthesized nanoconjugates against drug …

Design, fabrication and characterisation of drug-loaded vaginal films: State-of-the-art

F Notario-Pérez, R Cazorla-Luna, A Martín-Illana… - Journal of Controlled …, 2020 - Elsevier
Films have undoubtedly seen the most significant advances in their development in recent
years of all the pharmaceutical forms for the vaginal administration of drugs. Films combine …

[HTML][HTML] Optimized hydration dynamics in mucoadhesive xanthan-based trilayer vaginal films for the controlled release of tenofovir

A Martín-Illana, E Chinarro, R Cazorla-Luna… - Carbohydrate …, 2022 - Elsevier
Karaya gum, pectin and xanthan gum have been tested as candidates for manufacturing
mucoadhesive trilayer films containing ethylcellulose and chitosan for the vaginal …

Development of mucoadhesive vaginal films based on HPMC and zein as novel formulations to prevent sexual transmission of HIV

F Notario-Pérez, A Martín-Illana, R Cazorla-Luna… - International Journal of …, 2019 - Elsevier
Although vaginal films were initially developed for a fast release of the drug, with the
adequate formulation they can also be useful for sustained release. The latest strategies for …

Hesperetin loaded proposomal gel for topical antioxidant activity

VM Vaz, SR Jitta, R Verma, L Kumar - Journal of Drug Delivery Science and …, 2021 - Elsevier
The present study was aimed at formulating and evaluating hesperetin-loaded proposomal
gel for topical antioxidant activity. Hesperetin-loaded proposomes were first formulated and …

[HTML][HTML] Design, preparation and in vitro characterizations of fluconazole loaded nanostructured lipid carriers

AV Fernandes, CR Pydi, R Verma, J Jose… - Brazilian Journal of …, 2020 - SciELO Brasil
Present study was aimed to prepare and characterize fluconazole loaded nanostructured
lipid carriers (FLZ-NLCs) for the treatment of fungal infections. Fungal infections are …