Ovarian cancer remains the most fatal gynecologic malignancy worldwide due to delayed
diagnosis as well as recurrence and drug resistance. Thus, the development of new tumor …

Background Germ cell tumours are uniquely associated with the gametogenic tissues of
males and females. A feature of these cancers is that they can express genes that are …

Cancer cells have many abnormal characteristics enabling tumors to grow, spread, and
avoid immunologic and therapeutic destruction. Central to this is the innate ability of …

Background Cancer/testis (CT) genes have expression normally restricted to the testis, but
become activated during oncogenesis, so they have excellent potential as cancer-specific …

The synaptonemal complex is a higher‐ordered proteinaceous architecture formed between
homologous chromosomes. SYCP 3 is a major component of the lateral/axial elements in …

Tumors markers can be described as molecular products expressed by neoplasia tissues (
immunohistochemistry), or metabolized and secreted by tumor and characterized …

Background In breast cancer, as in all cancers, genetic and epigenetic deregulations can
result in out-of-context expressions of a set of normally silent tissue-specific genes. The …

No general property of organisms is of value in evolution under all environmental
circumstances, everything is context-dependent. Cooperation and competition can be …

Cancer is a highly complex disease that evolved in response to a wide range of biological
and molecular changes that impact disease behaviour, treatment efficacy and clinical …

The study of human embryonic stem cells (hESCs) and cancer cells in vitro is useful for
exploring the behaviour of cells employed in the development of regenerative medicine and …