The role of autophagy in bone metabolism and clinical significance

J Wang, Y Zhang, J Cao, Y Wang, N Anwar, Z Zhang… - Autophagy, 2023 - Taylor & Francis
The skeletal system is the basis of the vertebral body composition, which affords stabilization
sites for muscle attachment, protects vital organs, stores mineral ions, supplies places to the …

GelMA-based bioactive hydrogel scaffolds with multiple bone defect repair functions: therapeutic strategies and recent advances

B Zhou, X Jiang, X Zhou, W Tan, H Luo, S Lei… - Biomaterials …, 2023 - spj.science.org
Currently, the clinical treatment of critical bone defects attributed to various causes remains
a great challenge, and repairing these defects with synthetic bone substitutes is the most …

Regulating macrophage polarization in high glucose microenvironment using lithium‐modified bioglass‐hydrogel for diabetic bone regeneration

Z Wu, J Bai, G Ge, T Wang, S Feng… - Advanced …, 2022 - Wiley Online Library
Diabetes mellitus is a chronic metabolic disease with a proinflammatory microenvironment,
causing poor vascularization and bone regeneration. Due to the lack of effective therapy and …

Caffeic Acid‐Deferoxamine Self‐Polymerization Coating on Ti Implant Promotes Osteointegration by Synergetic Regulation of Multi‐Pathways in ONFH Mechanism

D Li, D Wang, Y Yang, P Gao, W Fan… - Advanced Functional …, 2023 - Wiley Online Library
Osteonecrosis of the femoral head (ONFH) is a common but sophisticated multifactorial
disease. In this study, the genomic characteristics of ONFH from the sequencing is first …

Biomimetic periodontal ligament transplantation activated by gold nanoparticles protects alveolar bone

C Zong, W Van Holm, A Bronckaers… - Advanced …, 2023 - Wiley Online Library
Stem cell therapy might be a promising method to stimulate alveolar bone regeneration,
which is currently a major clinical challenge. However, its therapeutic features largely …

[HTML][HTML] A general strategy for prepared multifunction double-ions agarose hydrogel dressing promotes wound healing

J Tian, J Peng, C Hu, S Lei, D Wu - Materials & Design, 2024 - Elsevier
In this study, a new multifunctional double-ions macro-porous agarose hydrogel dressing is
proposed, which successfully loaded Ag+ and Li+ simultaneously through the interaction of …

Hair and serum trace element and mineral levels profiles in women with premenopausal and postmenopausal osteoporosis

AV Skalny, TV Korobeinikova, M Aschner… - … Trace Element Research, 2024 - Springer
The objective of the present study was to evaluate serum and hair trace element and mineral
levels in women with osteoporosis, as well as to estimate the impact of menopausal status …

Alpha‐ketoglutarate up‐regulates autophagic activity in peri‐implant environment and enhances dental implant osseointegration in osteoporotic mice

R Liu, Y Gao, L Huang, B Shi, X Yin… - Journal of Clinical …, 2023 - Wiley Online Library
Aim The osseointegration of dental implants is impaired in patients with osteoporosis,
leading to significantly higher failure rates. This study set out to investigate the potential …

Lithium prevents glucocorticoid‑induced chondrocyte autophagy: An in vitro study

Q Wang, W Zhang, J Hu, C Zhao… - Molecular Medicine …, 2023 - spandidos-publications.com
Glucocorticoids can induce chondrocyte autophagy. Lithium is a classical regulator of
autophagy. The present study aimed to determine whether lithium can prevent …

Tideglusib enhances odontogenic differentiation in human dental pulp stem cells in vitro

C Kornsuthisopon, KA Tompkins… - International …, 2023 - Wiley Online Library
Aim Tideglusib is a small molecule agonist of the canonical Wnt pathway. The present study
investigated the influence of Tideglusib on human dental pulp stem cell (hDPSC) …