The recent availability of comprehensive, brain-wide gene expression atlases such as the
Allen Human Brain Atlas (AHBA) has opened new opportunities for understanding how …

Background Multiple alignments of mammalian genomes have been the basis of many
comparative genomic studies aiming at annotating genes, detecting regions under …

Mechanisms underlying α-synuclein (αSyn) mediated neurodegeneration are poorly
understood. Intramuscular (IM) injection of αSyn fibrils in human A53T transgenic M83+ …

Melatonin is a multifunctional signalling molecule that is secreted by the mammalian pineal
gland, and also found in a number of organisms including plants and bacteria. Research …

Obtaining valuable clues for noncoding RNA (ribonucleic acid) subsequences remains a
significant challenge, acknowledging that most of the human genome transcribes into …

Purpose: Based on our preview evidence that reduced nuclear content of the transcription
factor Myc-associated protein X (MAX) is an early event associated with degeneration of …

Aims Leptin irresponsiveness, which is often associated with obesity, can have significant
impacts on the hypothalamic proteome of individuals, including those who are lean. While …

The monoamine oxidase A (MAO-A) is integral to monoamine metabolism and is thus
relevant to the pathophysiology of various neuropsychiatric disorders; however, associated …

Glioblastoma multiforme (GBM) is an aggressive brain cancer with a very poor prognosis. It
has been shown that GBM stem cells within a GBM tumour have increased resistance to …

Conversion of mesenchymal stem cells (MSC) into neuron-like cells (NLC) is a feasible cell
therapy strategy for replacing lost neurons in neuronal disorders. In this study, adipose …