Deep brain stimulation of midbrain locomotor circuits in the freely moving pig
SJ Chang, AJ Santamaria, FJ Sanchez, LM Villamil… - Brain stimulation, 2021 - Elsevier
Background Deep brain stimulation (DBS) of the mesencephalic locomotor region (MLR)
has been studied as a therapeutic target in rodent models of stroke, parkinsonism, and …
has been studied as a therapeutic target in rodent models of stroke, parkinsonism, and …
Overground gait kinematics and muscle activation patterns in the Yucatan mini pig
S Mirkiani, DA Roszko, CL O'Sullivan… - Journal of Neural …, 2022 - iopscience.iop.org
Objective. The objectives of this study were to assess gait biomechanics and the effect of
overground walking speed on gait parameters, kinematics, and electromyographic (EMG) …
overground walking speed on gait parameters, kinematics, and electromyographic (EMG) …
Deep brain stimulation of the Cuneiform nucleus for levodopa-resistant freezing of gait in Parkinson's disease: study protocol for a prospective, pilot trial
Background Freezing of gait (FOG) is a particularly debilitating motor deficit seen in a subset
of Parkinson's disease (PD) patients that is poorly responsive to standard levodopa therapy …
of Parkinson's disease (PD) patients that is poorly responsive to standard levodopa therapy …
In vivo Population Averaged Stereotaxic T2w MRI Brain Template for the Adult Yucatan Micropig
SJ Chang, AJ Santamaria, FJ Sanchez… - Frontiers in …, 2020 - frontiersin.org
Population averaged brain templates are an essential tool for imaging-based neuroscience
research, providing investigators with information about the expected size and morphology …
research, providing investigators with information about the expected size and morphology …
MR Tractography-based targeting and physiological identification of the cuneiform nucleus for directional DBS in a Parkinson's disease patient with levodopa-resistant …
Background Freezing of gait (FOG) is a debilitating motor deficit in a subset of Parkinson's
Disease (PD) patients that is poorly responsive to levodopa or deep brain stimulation (DBS) …
Disease (PD) patients that is poorly responsive to levodopa or deep brain stimulation (DBS) …
Safety of mapping the motor networks in the spinal cord using penetrating microelectrodes in Yucatan minipigs
S Mirkiani, CL O'Sullivan, DA Roszko, P Faridi… - … of Neurosurgery: Spine, 2024 - thejns.org
OBJECTIVE The goal of this study was to assess the safety of mapping spinal cord
locomotor networks using penetrating stimulation microelectrodes in Yucatan minipigs …
locomotor networks using penetrating stimulation microelectrodes in Yucatan minipigs …
[PDF][PDF] Results: Post-operative imaging revealed accurate targeting of both leads to the designated CnF. Intraoperative stimulation near the target at low thresholds in …
Background: Freezing of gait (FOG) is a debilitating motor deficit in a subset of Parkinson's
Disease (PD) patients that is poorly responsive to levodopa or deep brain stimulation (DBS) …
Disease (PD) patients that is poorly responsive to levodopa or deep brain stimulation (DBS) …
[PDF][PDF] Enhancing Locomotor Function through Combined Mesencephalic Locomotor Region Stimulation and Epidural Stimulation in a Large Animal Model of Thoracic …
SJ Chang - 2021 - scholarship.miami.edu
Paralysis, loss of gait function, and reduced mobility are devastating and lifealtering
consequences of spinal cord injury (SCI) that not only reduce quality of life, but have …
consequences of spinal cord injury (SCI) that not only reduce quality of life, but have …