Simple Summary The epithelial to mesenchymal transition (EMT) is a well-documented
process in the study of cancer metastases. The cytoskeleton is an intricate network involved …

Microtubules are highly dynamic structures, which consist of α-and β-tubulin heterodimers,
and are involved in cell movement, intracellular trafficking, and mitosis. In the context of …

Microtubules are dynamic structures composed of α–β-tubulin heterodimers that are
essential in cell division and are important targets for cancer drugs. Mutations in β-tubulin …

Apoptosis is an important biological process required for the removal of unwanted or
damaged cells. Mounting evidence implicates the actin cytoskeleton as both a sensor and …

Tubulin proteins, as components of the microtubule cytoskeleton perform critical cellular
functions throughout all phases of the cell cycle. Altered tubulin isotype composition of …

The tubulin/microtubule system is an important target for anticancer therapy. Two of the most
clinically valuable groups of these agents are the vinca alkaloids and taxanes. In recent …

Natural products have proven to be promising anti-cancer agents due to their diverse
chemical structures and bioactivity. This review examines their central role in cancer …

Quinolinate (Quin) is a classic example of a biochemical double-edged sword, acting as
both essential metabolite and potent neurotoxin. Quin is an important metabolite in the …

Many actin‐binding proteins are expressed in eukaryotic cells. These polypep‐tides assist in
stabilizing and rearranging the organization of the actin cytoskeleton in response to external …

Childhood acute lymphoblastic leukemia (ALL) consists of various subtypes that respond
differently to cytotoxic drugs and therefore have a markedly different clinical outcome. We …