Understanding tissue injury and remodelling in eosinophilic oesophagitis: development towards personalised medicine

G Santacroce, CM Rossi, MV Lenti, S Ghosh, M Iacucci… - Gut, 2024 - gut.bmj.com
Eosinophilic oesophagitis (EoE) is a chronic, immune-mediated condition characterised by
eosinophilic infiltration of the oesophagus, leading to significant morbidity due to …

Advances and Ongoing Challenges in Eosinophilic Gastrointestinal Disorders presented at the CEGIR/TIGERS Symposium at the 2024 American Academy of Allergy …

BL Wright, JP Abonia, EM Abud, SS Aceves… - Journal of Allergy and …, 2024 - Elsevier
Abstract The Consortium of Eosinophilic Gastrointestinal disease Researchers (CEGIR) and
The International Gastrointestinal Eosinophil Researchers (TIGERS) organized a day-long …

[HTML][HTML] Lysyl Oxidase Mediates Proliferation and Differentiation in the Esophageal Epithelium

KV Kennedy, JX Wang, E McMillan, Y Zhou… - Biomolecules, 2024 - mdpi.com
In homeostatic conditions, the basal progenitor cells of the esophagus differentiate into a
stratified squamous epithelium. However, in the setting of acid exposure or inflammation …

PI3K signaling and lysyl oxidase is critical to corneal stroma fibrosis following mustard gas injury

NR Sinha, AC Hofmann, LA Suleiman, R Laub… - Experimental Eye …, 2025 - Elsevier
Sulfur mustard gas (SM), an alkylating and vesicating agent, has been used frequently in
many wars and conflicts. SM exposure to the eye results in several corneal abnormalities …

[HTML][HTML] Epithelial-fibroblast crosstalk in eosinophilic esophagitis

AB Muir, TA Karakasheva, KA Whelan - Cellular and Molecular …, 2024 - Elsevier
Eosinophilic esophagitis (EoE) is an emerging form of food allergy that exerts a significant
clinical and financial burden worldwide. EoE is clinically characterized by eosinophil-rich …

Development and dysfunction of structural cells in eosinophilic esophagitis

K Laky, PA Frischmeyer-Guerrerio - Journal of Allergy and Clinical …, 2024 - Elsevier
Eosinophilic esophagitis (EoE) is a disorder characterized by dysfunction and chronic local
inflammation of the esophagus. The incidence and prevalence of EoE are increasing …

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

T Kaymak, JH Niess - JoVE (Journal of Visualized Experiments), 2024 - jove.com
The squamous epithelium of the esophagus is directly exposed to the environment,
continuously facing foreign antigens, including food antigens and microbes. Maintaining the …

[HTML][HTML] Three-Dimensional Cell Culture Models to Investigate the Epithelial Barrier in Eosinophilic Esophagitis

T Kaymak, JH Niess - JoVE (Journal …, 2024 - www-jove-com-443.vpn.cdutcm.edu …
The squamous epithelium of the esophagus is directly exposed to the environment,
continuously facing foreign antigens, including food antigens and microbes. Maintaining the …