Microfluidic platforms for extracellular vesicle isolation, analysis and therapy in cancer

CM Abreu, B Costa-Silva, RL Reis, SC Kundu… - Lab on a Chip, 2022 - pubs.rsc.org
Extracellular vesicles (EVs) are small lipidic particles packed with proteins, DNA, messenger
RNA and microRNAs of their cell of origin that act as critical players in cell–cell …

Reaching silicon-based NEMS performances with 3D printed nanomechanical resonators

S Stassi, I Cooperstein, M Tortello, CF Pirri… - Nature …, 2021 - nature.com
The extreme miniaturization in NEMS resonators offers the possibility to reach an
unprecedented resolution in high-performance mass sensing. These very low limits of …

Magnetic flexible tactile sensor via direct ink writing

X Zhang, H Hu, D Tang, C Zhang, J Fu… - Sensors and Actuators A …, 2021 - Elsevier
The development of flexible tactile sensors is an emerging field due to their wide
applications ranging from human-robot interactions to wearable electronics. This paper …

High-throughput determination of dry mass of single bacterial cells by ultrathin membrane resonators

A Sanz-Jiménez, O Malvar, JJ Ruz… - Communications …, 2022 - nature.com
How bacteria are able to maintain their size remains an open question. Techniques that can
measure the biomass (dry mass) of single cells with high precision and high-throughput are …

Fabricating silicon resonators for analysing biological samples

M Kumemura, D Pekin, VA Menon, I Van Seuningen… - Micromachines, 2021 - mdpi.com
The adaptability of microscale devices allows microtechnologies to be used for a wide range
of applications. Biology and medicine are among those fields that, in recent decades, have …

Weighing the DNA content of Adeno-Associated Virus vectors with zeptogram precision using nanomechanical resonators

G Katsikis, IE Hwang, W Wang, VS Bhat… - Nano Letters, 2022 - ACS Publications
Quantifying the composition of viral vectors used in vaccine development and gene therapy
is critical for assessing their functionality. Adeno-associated virus (AAV) vectors, which are …

Avoiding transduction-induced heating in suspended microchannel resonators using piezoelectricity

D Maillard, A De Pastina, AM Abazari… - Microsystems & …, 2021 - nature.com
Calorimetry of single biological entities remains elusive. Suspended microchannel
resonators (SMRs) offer excellent performance for real-time detection of various analytes …

Sub‐Nanogram Resolution Measurement of Inertial Mass and Density Using Magnetic‐Field‐Guided Bubble Microthruster

L Wang, M Sheng, L Chen, F Yang, C Li, H Li… - Advanced …, 2024 - Wiley Online Library
Artificial micro/nanomotors using active particles hold vast potential in applications such as
drug delivery and microfabrication. However, upgrading them to micro/nanorobots capable …

Measuring nanoparticles in liquid with attogram resolution using a microfabricated glass suspended microchannel resonator

MM Daryani, T Manzaneque, J Wei… - Microsystems & …, 2022 - nature.com
The use of nanoparticles has been growing in various industrial fields, and concerns about
their effects on health and the environment have been increasing. Hence, characterization …

Nanomass sensing via node shift tracing in vibrations of coupled nanowires enhanced by fano resonances

A Mozharov, Y Berdnikov, N Solomonov… - ACS Applied Nano …, 2021 - ACS Publications
We suggest an approach to mass sensing via tracing the shift of the node position as an
alternative to current sensing approaches based on the detection of the frequency shift. We …