The endocrine disruptor bisphenol A (BPA) exerts a wide range of effects in carcinogenesis and response to therapy

SA Hafezi, WM Abdel-Rahman - Current molecular …, 2019 - ingentaconnect.com
Background: Bisphenol A (BPA) is a synthetic plasticizer that is commonly used in the
production of polycarbonate plastics and epoxy resins. Human exposure occurs when BPA …

Potential of the miR-200 family as a target for developing anti-cancer therapeutics

H Jo, K Shim, D Jeoung - International Journal of Molecular Sciences, 2022 - mdpi.com
MicroRNAs (miRNAs) are small non-coding RNAs (18–24 nucleotides) that play significant
roles in cell proliferation, development, invasion, cancer development, cancer progression …

FBXW2 suppresses breast tumorigenesis by targeting AKT-Moesin-SKP2 axis

GK Barik, O Sahay, A Mukhopadhyay, RK Manne… - Cell Death & …, 2023 - nature.com
Oncogene Moesin plays critical role in initiation, progression, and metastasis of multiple
cancers. It exerts oncogenic activity due to its high-level expression as well as …

Roles of miR-200 family members in lung cancer: more than tumor suppressors

C Liu, W Hu, LL Li, YX Wang, Q Zhou, F Zhang… - Future …, 2018 - Taylor & Francis
miRNAs are a class of single-stranded noncoding RNAs, which have no coding potential,
but modulate many molecular mechanisms including cancer pathogenesis. miRNAs …

The role of microRNAs on doxorubicin drug resistance in breast cancer

K Jamialahmadi, F Zahedipour… - Journal of Pharmacy and …, 2021 - academic.oup.com
Objectives Resistance to chemotherapeutic drugs is a serious challenge for effective therapy
of cancers. Doxorubicin is a drug which is typically used for breast cancer treatment. Several …

[HTML][HTML] Elevated GCN5 expression confers tamoxifen resistance by upregulating AIB1 expression in ER-positive breast cancer

JH Oh, JY Lee, KH Kim, CY Kim, Y Cho, KT Nam… - Cancer Letters, 2020 - Elsevier
Approximately 70% of breast cancers are estrogen receptor (ER)-positive and treated with
endocrine therapy. A commonly used treatment agent, tamoxifen, shows high efficacy for …

Metformin impairs cisplatin resistance effects in A549 lung cancer cells through mTOR signaling and other metabolic pathways

AP Morelli, TC Tortelli Jr… - International …, 2021 - spandidos-publications.com
Lung cancer is the leading cause of cancer‑associated death worldwide and exhibits
intrinsic and acquired therapeutic resistance to cisplatin (CIS). The present study …

Identification of Moesin (MSN) as a potential therapeutic target for colorectal cancer via the Β-Catenin-Runx2 axis

CY Huang, PL Wei, U Batzorig, PT Makondi… - International journal of …, 2023 - mdpi.com
CRC is the second leading cause of cancer-related death. The complex mechanisms of
metastatic CRC limit available therapeutic choice. Thus, identifying new CRC therapeutic …

Pollutants, microbiota and immune system: frenemies within the gut

P Rio, A Gasbarrini, G Gambassi, R Cianci - Frontiers in Public Health, 2024 - frontiersin.org
Pollution is a critical concern of modern society for its heterogeneous effects on human
health, despite a widespread lack of awareness. Environmental pollutants promote several …

Cancer-associated stemness and epithelial-to-mesenchymal transition signatures related to breast invasive carcinoma prognostic

IM Groza, C Braicu, A Jurj, O Zanoaga, R Lajos… - Cancers, 2020 - mdpi.com
Simple Summary Breast cancer is one of the most common oncological diseases in women,
as its incidence is rapidly growing. In this study, we have investigated the mechanism of …