Clinical and imaging assessment of cognitive dysfunction in multiple sclerosis

MA Rocca, MP Amato, N De Stefano… - The Lancet …, 2015 - thelancet.com
In patients with multiple sclerosis (MS), grey matter damage is widespread and might
underlie many of the clinical symptoms, especially cognitive impairment. This relation …

Treatment and management of cognitive dysfunction in patients with multiple sclerosis

J DeLuca, ND Chiaravalloti, BM Sandroff - Nature Reviews Neurology, 2020 - nature.com
Cognitive impairment is a common and devastating manifestation of multiple sclerosis (MS).
Although disease-modifying therapies have been efficacious for reducing relapse rates in …

Meta-analytic evidence for a superordinate cognitive control network subserving diverse executive functions

TA Niendam, AR Laird, KL Ray, YM Dean… - Cognitive, Affective, & …, 2012 - Springer
Classic cognitive theory conceptualizes executive functions as involving multiple specific
domains, including initiation, inhibition, working memory, flexibility, planning, and vigilance …

Cognitive impairment in multiple sclerosis

ND Chiaravalloti, J DeLuca - The Lancet Neurology, 2008 - thelancet.com
Multiple sclerosis (MS) is a progressive disease of the CNS that is characterised by
widespread lesions in the brain and spinal cord. MS results in motor, cognitive, and …

The contribution of MRI in assessing cognitive impairment in multiple sclerosis

M Filippi, MA Rocca, RHB Benedict, J DeLuca… - Neurology, 2010 - AAN Enterprises
Cognitive impairment affects a large proportion of patients with multiple sclerosis (MS) and
has a profound impact on their daily-life activities. Improving the knowledge of the …

[HTML][HTML] Task-and resting-state fMRI studies in multiple sclerosis: From regions to systems and time-varying analysis. Current status and future perspective

MA Rocca, MM Schoonheim, P Valsasina… - Neuroimage: Clinical, 2022 - Elsevier
Multiple sclerosis (MS) is a neurological disorder affecting the central nervous system and
features extensive functional brain changes that are poorly understood but relate strongly to …

Hidden dysfunctioning in subacute stroke

A Jaillard, B Naegele, S Trabucco-Miguel, JF LeBas… - Stroke, 2009 - Am Heart Assoc
Background and Purpose—Determining cognitive dysfunctioning (CDF) after stroke is an
important issue because it influences choices for management in terms of return to previous …

Distributed changes in default-mode resting-state connectivity in multiple sclerosis

S Bonavita, A Gallo, R Sacco, MD Corte… - Multiple sclerosis …, 2011 - journals.sagepub.com
Background: The default-mode network (DMN) has been increasingly recognized as
relevant to cognitive status. Objectives: To explore DMN changes in patients with relapsing …

Neuroplasticity and functional recovery in multiple sclerosis

V Tomassini, PM Matthews, AJ Thompson… - Nature Reviews …, 2012 - nature.com
The development of therapeutic strategies that promote functional recovery is a major goal
of multiple sclerosis (MS) research. Neuroscientific and methodological advances have …

MRI of the corpus callosum in multiple sclerosis: association with disability

A Ozturk, SA Smith, EM Gordon-Lipkin… - Multiple Sclerosis …, 2010 - journals.sagepub.com
Inflammatory demyelination and axon damage in the corpus callosum are prominent
features of multiple sclerosis (MS) and may partially account for impaired performance on …