Influenza viruses: harnessing the crucial role of the M2 ion-channel and neuraminidase toward inhibitor design
As a member of the Orthomyxoviridae family of viruses, influenza viruses (IVs) are known
causative agents of respiratory infection in vertebrates. They remain a major global threat …
causative agents of respiratory infection in vertebrates. They remain a major global threat …
Unmasking the potential of secretory IgA and its pivotal role in protection from respiratory viruses
D Sinha, M Yaugel-Novoa, L Waeckel, S Paul… - Antiviral Research, 2024 - Elsevier
Mucosal immunity has regained its spotlight amidst the ongoing Coronavirus Disease 19
(COVID-19) pandemic, with numerous studies highlighting the crucial role of mucosal …
(COVID-19) pandemic, with numerous studies highlighting the crucial role of mucosal …
Immune responses elicited by live attenuated influenza vaccines as correlates of universal protection against influenza viruses
YH Jang, BL Seong - Vaccines, 2021 - mdpi.com
Influenza virus infection remains a major public health challenge, causing significant
morbidity and mortality by annual epidemics and intermittent pandemics. Although current …
morbidity and mortality by annual epidemics and intermittent pandemics. Although current …
[HTML][HTML] Induction of Tier 2 HIV-Neutralizing IgA Antibodies in Rhesus Macaques Vaccinated with BG505. 664 SOSIP
JC Smith, PS Arunachalam, TH Legere, LA Cavacini… - Vaccines, 2024 - mdpi.com
Background: A goal of mucosal human immunodeficiency virus type 1 (HIV-1) vaccines is to
generate mucosal plasma cells producing polymeric IgA (pIgA)-neutralizing antibodies at …
generate mucosal plasma cells producing polymeric IgA (pIgA)-neutralizing antibodies at …
YWHAG inhibits influenza a virus replication by suppressing the release of viral M2 protein
H Mao, L Cao, T Xu, X Xia, P Ren, P Han, C Li… - Frontiers in …, 2022 - frontiersin.org
Influenza A virus (IAV) poses a serious threat to human life and property. The IAV matrix
protein 2 (M2) is significant in viral budding. Increasing studies have proven the important …
protein 2 (M2) is significant in viral budding. Increasing studies have proven the important …
Comprehensive analysis of nasal IgA antibodies induced by intranasal administration of the SARS-CoV-2 spike protein
K Waki, H Tani, Y Saga, T Shimada, E Yamazaki… - bioRxiv, 2023 - biorxiv.org
Intranasal vaccination is an attractive strategy for preventing COVID-19 disease as it
stimulates the production of multimeric secretory immunoglobulin A (IgAs), the predominant …
stimulates the production of multimeric secretory immunoglobulin A (IgAs), the predominant …