Purpose To perform a systematic review and meta-analysis to estimate the diagnostic
performance of breast proton magnetic resonance (MR) spectroscopy in differentiating …

In vivo 1H MRS is rapidly developing as a clinical tool for diagnosing and characterizing
breast cancers. Many in vivo and in vitro experiments have demonstrated that alterations in …

Purpose: Glutamine addiction in c-MYC–overexpressing breast cancer is targeted by the
aminotransferase inhibitor, aminooxyacetate (AOA). However, the mechanism of ensuing …

Purpose: To compare changes in the concentration of choline-containing compounds (tCho)
and in tumor size at follow-up after neoadjuvant chemotherapy (NAC) between patients who …

Choline phospholipid metabolism is altered in a wide variety of cancers. The choline
metabolite profile of tumors and cancer cells is characterized by an elevation of …

Proton magnetic resonance spectroscopy (MRS) is a promising noninvasive diagnostic
technique for investigation of breast cancer metabolism. Spectroscopic imaging data may be …

Since its discovery in the 1940s, magnetic resonance spectroscopy (MRS) has developed
into a major technique used by chemists to elucidate molecular structures. The underlying …

OBJECTIVE. The purpose of our study was to use the total choline-containing compound
(tCho) peak integral as a marker of malignancy in breast MR spectroscopy (MRS) …

An emerging clinical modality called proton magnetic resonance spectroscopy (1 H-MRS)
enables the non-invasive in vivo assessment of tissue metabolism and is demonstrating …

MRS and MRSI are valuable tools for the detection of metabolic changes in tumors. The
currently emerging era of molecular medicine, which is shaped by molecularly targeted …