International Union of Basic and Clinical Pharmacology. CX. Classification of receptors for 5-hydroxytryptamine; pharmacology and function

NM Barnes, GP Ahern, C Becamel, J Bockaert… - Pharmacological …, 2021 - Elsevier
HT receptors expressed throughout the human body are targets for established therapeutics
and various drugs in development. Their diversity of structure and function reflects the …

A review of central 5-HT receptors and their function

NM Barnes, T Sharp - Neuropharmacology, 1999 - Elsevier
It is now nearly 5 years since the last of the currently recognised 5-HT receptors was
identified in terms of its cDNA sequence. Over this period, much effort has been directed …

Molecular, pharmacological and functional diversity of 5-HT receptors

D Hoyer, JP Hannon, GR Martin - Pharmacology Biochemistry and …, 2002 - Elsevier
Serotonin (5-hydroxytryptamine, 5-HT) is probably unique among the monoamines in that its
effects are subserved by as many as 13 distinct heptahelical, G-protein-coupled receptors …

Molecular biology of 5-HT receptors

J Hannon, D Hoyer - Behavioural brain research, 2008 - Elsevier
Serotonin (5-hydroxytryptamine; 5-HT) is a monoamine neurotransmitter whose effects are
mediated by at least 13 distinct G protein-coupled receptors (GPCRs) of the type A family …

Aripiprazole, a novel atypical antipsychotic drug with a unique and robust pharmacology

DA Shapiro, S Renock, E Arrington… - …, 2003 - nature.com
Atypical antipsychotic drugs have revolutionized the treatment of schizophrenia and related
disorders. The current clinically approved atypical antipsychotic drugs are characterized by …

Pharmacognostic and pharmacological profile of Humulus lupulus L.

P Zanoli, M Zavatti - Journal of ethnopharmacology, 2008 - Elsevier
The present review describes the morphological, phytochemical and ethnopharmacological
aspects of Humulus lupulus L.(Cannabinaceae) and summarizes the most interesting …

Multiplicity of mechanisms of serotonin receptor signal transduction

JR Raymond, YV Mukhin, A Gelasco, J Turner… - Pharmacology & …, 2001 - Elsevier
The serotonin (5-hydroxytryptamine, 5-HT) receptors have been divided into 7 subfamilies
by convention, 6 of which include 13 different genes for G-protein-coupled receptors. Those …

Rewiring of the serotonin system in major depression

F Vahid-Ansari, PR Albert - Frontiers in psychiatry, 2021 - frontiersin.org
Serotonin is a key neurotransmitter that is implicated in a wide variety of behavioral and
cognitive phenotypes. Originating in the raphe nuclei, 5-HT neurons project widely to …

The multiplicity of serotonin receptors: uselessly diverse molecules or an embarrassment of riches?

BL Roth, E Lopez, S Patel, WK Kroeze - The Neuroscientist, 2000 - journals.sagepub.com
A large number of 5-HT receptors (> 15) have been identified by molecular cloning
technology over the past 10 years. This review briefly summarizes available information …

Interactions of the novel antipsychotic aripiprazole (OPC-14597) with dopamine and serotonin receptor subtypes

CP Lawler, C Prioleau, MM Lewis, C Mak… - …, 1999 - Elsevier
OPC-14597 {aripiprazole; 7-(4-(4-(2, 3-dichlorophenyl)-1-piperazinyl) butyloxy)-3, 4-dihydro-
2 (1H)-quinolinone} is a novel candidate antipsychotic that has high affinity for striatal …