[HTML][HTML] Exploring the potential of endophytes from medicinal plants as sources of antimycobacterial compounds

A Alvin, KI Miller, BA Neilan - Microbiological research, 2014 - Elsevier
Natural product drug discovery has regained interest due to low production costs, structural
diversity, and multiple uses of active compounds to treat various diseases. Attention has …

Dereplication strategies in natural product research: How many tools and methodologies behind the same concept?

J Hubert, JM Nuzillard, JH Renault - Phytochemistry Reviews, 2017 - Springer
The development of new drugs will certainly benefit from an ever improving knowledge of
the living beings chemistry. However, identification of drugable molecules within the …

Harnessing the intracellular triacylglycerols for titer improvement of polyketides in Streptomyces

W Wang, S Li, Z Li, J Zhang, K Fan, G Tan, G Ai… - Nature …, 2020 - nature.com
Pharmaceutically important polyketides such as avermectin are mainly produced as
secondary metabolites during the stationary phase of growth of Streptomyces species in …

Marine pharmacology in 2009–2011: Marine compounds with antibacterial, antidiabetic, antifungal, anti-inflammatory, antiprotozoal, antituberculosis, and antiviral …

AMS Mayer, AD Rodríguez, O Taglialatela-Scafati… - Marine drugs, 2013 - mdpi.com
The peer-reviewed marine pharmacology literature from 2009 to 2011 is presented in this
review, following the format used in the 1998–2008 reviews of this series. The …

Dereplication: racing to speed up the natural products discovery process

SP Gaudêncio, F Pereira - Natural product reports, 2015 - pubs.rsc.org
Covering: 1993–2014 (July) To alleviate the dereplication holdup, which is a major
bottleneck in natural products discovery, scientists have been conducting their research …

Bioprospecting sponge-associated microbes for antimicrobial compounds

AAG Indraningrat, H Smidt, D Sipkema - Marine drugs, 2016 - mdpi.com
Sponges are the most prolific marine organisms with respect to their arsenal of bioactive
compounds including antimicrobials. However, the majority of these substances are …

Bovine mastitis: An appraisal of its alternative herbal cure

S Mushtaq, AM Shah, A Shah, SA Lone, A Hussain… - Microbial …, 2018 - Elsevier
Highlights•Bovine mastitis is the most common and costly disease affecting dairy
herds.•Antibacterial agents are associated with the problem of antibiotic resistance.•Herbal …

Marine polysaccharides in pharmaceutical applications: Fucoidan and chitosan as key players in the drug delivery match field

AI Barbosa, AJ Coutinho, SA Costa Lima, S Reis - Marine Drugs, 2019 - mdpi.com
The use of marine-origin polysaccharides has increased in recent research because they
are abundant, cheap, biocompatible, and biodegradable. These features motivate their …

Synergistic combinations of antifungals and anti-virulence agents to fight against Candida albicans

J Cui, B Ren, Y Tong, H Dai, L Zhang - Virulence, 2015 - Taylor & Francis
Candida albicans, one of the pathogenic Candida species, causes high mortality rate in
immunocompromised and high-risk surgical patients. In the last decade, only one new class …

Abyssomicins from the South China Sea Deep‐Sea Sediment Verrucosispora sp.: Natural Thioether Michael Addition Adducts as Antitubercular Prodrugs

Q Wang, F Song, X Xiao, P Huang, L Li… - Angewandte Chemie …, 2013 - Wiley Online Library
Tuberculosis (TB) is a leading cause of death in the world today, and is exacerbated by the
prevalence of multi-(MDRTB), extensively (XDR-TB), and totally (TDR-TB) drug resistant …