The crucial role of cancer stem cells (CSC s) in the pathology of malignant diseases has
been extensively studied during the last decade. Nestin, a class VI intermediate filament …

Despite great strides being achieved in improving cancer patients' outcomes through better
therapies and combinatorial treatment, several hurdles still remain due to therapy …

Adult-type fibrosarcoma is a rare and highly aggressive subtype of soft tissue sarcomas. Due
to the existence of other spindle-cell shaped sarcomas, its diagnosis is always one of …

Sarcomas represent an extensive group of divergent malignant diseases, with the only
common characteristic of being derived from mesenchymal cells. As such, sarcomas are by …

Sarcoma is the collective name for a relatively rare, yet heterogeneous group of cancers,
most probably derived from mesenchymal tissues. There are currently over 50 sarcoma …

Cancer is one amongst the major causes of death today and cancer biology is one of the
most well researched fields in medicine. The driving force behind cancer is considered to be …

The three most frequent pediatric sarcomas, ie, Ewing's sarcoma, osteosarcoma, and
rhabdomyosarcoma, were examined in this study: three cell lines derived from three primary …

Sarcomas are a heterogeneous group of malignant neoplasms of mesenchymal origin,
many of which have a propensity to develop distant metastases. Cancer cells that have …

Background Sarcomas are rare tumors but represent the third most common malignancy in
children. The cancer stem cell (CSC) paradigm is well established, and CSCs have been …

Background Sarcomas are a very heterogeneous group of tumors with intrinsic
developmental programs derived from the cell of origin. This implies a functional hierarchy …