Mechanistic insight into immunomodulatory effects of food-functioned plant secondary metabolites

ASM Ali Reza, MS Nasrin, MA Hossen… - Critical reviews in …, 2023 - Taylor & Francis
Medicinally important plant-foods offer a balanced immune function, which is essential for
protecting the body against antigenic invasion, mainly by microorganisms …

A review on the antimicrobial properties of lectins

VJA Fonseca, AL Braga, J Ribeiro Filho… - International journal of …, 2022 - Elsevier
Lectins are biologically versatile biomolecules with remarkable antimicrobial effects, notably
against bacteria, fungi and protozoa, in addition to modulating host immunity. For this, the …

Concanavalin A, lectin from Canavalia ensiformis seeds has Leishmania infantum antipromastigote activity mediated by carbohydrate recognition domain

ALE Dos Santos, ROS Souza, FEV Barbosa… - Chemico-Biological …, 2024 - Elsevier
Leishmaniases, caused by Leishmania parasites, are widespread and pose significant
health risks globally. Visceral leishmaniasis (VL) is particularly prevalent in Brazil, with high …

Biogenic silver nanoparticles (AgNp-Bio) reduce Toxoplasma gondii infection and proliferation in HeLa cells, and induce autophagy and death of tachyzoites by …

RA da Silva Sanfelice, BT da Silva Bortoleti… - Acta Tropica, 2021 - Elsevier
Toxoplasma gondii is a protozoan parasite that can cause severe and debilitating diseases,
especially in immunocompromised individuals. The available treatment is based on drugs …

Lectins as the prominent potential to deliver bioactive metal nanoparticles by recognizing cell surface glycans

SB Subramaniyan, A Veerappan - Heliyon, 2024 - cell.com
Lectins are renowned for recognizing specific carbohydrates, but there is evidence that they
can bind to other endogenous ligands. Therefore, lectin can be used as a carrier to …

Concanavalin-A stimulates IL-17 and nitric oxide production and induces macrophage polarization and resistance to Trypanosoma cruzi infection

NG Zanluqui, MI Lovo-Martins, AD Malvezi, C Panis… - Life Sciences, 2020 - Elsevier
Aims Chagas disease is a neglected tropical disease. The ability of Trypanosoma cruzi to
survive within phagocytes is likely a critical factor for T. cruzi dissemination in the host. For …

Insect galectin stimulates the human CD4+ T cell proliferation by regulating inflammation (T cell and monocyte) through Th2 immune response

S Bhuvaragavan, K Sruthi, R Nivetha, P Ramaraj… - Process …, 2023 - Elsevier
In this study, the galectin (OrGal) was purified from the grub of rhinoceros beetle (Oryctes
rhinoceros)(Coleoptera: Scarabaeidae) using lactose-affinity chromatography and its …

Microgramma vacciniifolia Frond Lectin: In Vitro Anti-leishmanial Activity and Immunomodulatory Effects Against Internalized Amastigote Forms of Leishmania …

LM de Souza Aguiar, MM de Moraes Alves… - Acta Parasitologica, 2023 - Springer
Purpose The treatment of leishmaniasis, an anthropozoonosis caused by Leishmania
protozoa, is limited by factors, such as adverse effects, toxicity, and excessive cost, which …

Enriched PUFA environment of Leishmania infantum promastigotes promotes the accumulation of lipid mediators and favors parasite infectivity towards J774 murine …

M Leroux, H Bouazizi‐Ben Messaoud… - Lipids, 2023 - Wiley Online Library
Leishmania parasites are the causative agents of visceral or cutaneous leishmaniasis in
humans and of canine leishmaniosis. The macrophage is the predilected host cell of …

Lupinus mutabilis Sweet (Tarwi) γ-conglutin Modulates TNF-α and IL-1α Transcriptional Expression in Human Monocytes Infected with Leishmania (V.) peruviana

R Arone-Farfán, L Alzamora-Gonzales… - Legume …, 2024 - indianjournals.com
Background γ-Conglutin is a hemagglutinating lectin found in the seeds of the Andean
legume Lupinus mutabilis. Leishmania (Viannia) peruviana is the etiological agent of …