Codon usage bias is the preferential or non-random use of synonymous codons, a
ubiquitous phenomenon observed in bacteria, plants and animals. Different species have …

Severe acute respiratory syndrome coronavirus-2 (SARS-CoV-2) belongs to the group of
Betacoronaviruses. The SARS-CoV-2 is closely related to SARS-CoV-1 and probably …

Programmed ribosomal frameshifting is a key event during translation of the severe acute
respiratory syndrome coronavirus 2 (SARS-CoV-2) RNA genome that allows synthesis of the …

Approximately 17 years after the severe acute respiratory syndrome coronavirus (SARS-
CoV) epidemic, the world is currently facing the COVID-19 pandemic caused by SARS …

The ribosome-associated protein quality control (RQC) system that resolves stalled
translation events is activated when ribosomes collide and form disome, trisome, or higher …

ATPases associated with diverse cellular activities (AAA+ proteins) are a superfamily of
proteins found throughout all domains of life. The hallmark of this family is a conserved …

In the modern genomic era, scientists without extensive bioinformatic training need to apply
high-power computational analyses to critical tasks like phage genome annotation. At the …

Efforts to precisely identify tumor human leukocyte antigen (HLA) bound peptides capable of
mediating T cell-based tumor rejection still face important challenges. Recent studies …

Frameshifting is an essential mechanism employed by many viruses including
coronaviruses to produce viral proteins from a compact RNA genome. It is facilitated by …

RNA viruses have very compact genomes and so provide a unique opportunity to study how
evolution works to optimize the use of very limited genomic information. A widespread viral …