[HTML][HTML] Cervical carcinoma: oncobiology and biomarkers

LV Volkova, AI Pashov, NN Omelchuk - International journal of molecular …, 2021 - mdpi.com
Cervical cancer is one of the most common types of carcinomas causing morbidity and
mortality in women in all countries of the world. At the moment, the oncology, oncobiology …

[HTML][HTML] The role of the cervicovaginal microbiome on the genesis and as a biomarker of premalignant cervical intraepithelial neoplasia and invasive cervical cancer

G Curty, PS de Carvalho, MA Soares - International journal of molecular …, 2019 - mdpi.com
The microbiome is able to modulate immune responses, alter the physiology of the human
organism, and increase the risk of viral infections and development of diseases such as …

[HTML][HTML] Involvement of human papillomaviruses in cervical cancer

X Wang, X Huang, Y Zhang - Frontiers in microbiology, 2018 - frontiersin.org
Human papillomaviruses (HPV) are the first viruses to have been acknowledged to prompt
carcinogenesis, and they are linked with cancers of the uterine cervix, anogenital tumors …

Understanding the HPV integration and its progression to cervical cancer

MA Oyervides-Muñoz, AA Pérez-Maya… - Infection, Genetics and …, 2018 - Elsevier
Cervical cancer is one of the main causes of female cancer death worldwide, and human
papilloma virus (HPV) its causal agent. To investigate viral oncogenesis several studies …

Molecular landscape of recurrent cervical cancer

D Adiga, S Eswaran, D Pandey, K Sharan… - Critical Reviews in …, 2021 - Elsevier
Cervical cancer (CC) is a major gynecological problem in developing and underdeveloped
countries. Despite the significant advancement in early detection and treatment modalities …

Methylation Analysis of the FAM19A4 Gene in Cervical Scrapes Is Highly Efficient in Detecting Cervical Carcinomas and Advanced CIN2/3 Lesions

LMA De Strooper, CJLM Meijer, J Berkhof… - Cancer Prevention …, 2014 - AACR
Primary testing for human papillomavirus (HPV) in cervical screening requires triage to
differentiate women with transient infection from those with persistent infection who require …

Cervical cancer risk in HPV‐positive women after a negative FAM19A4/mir124‐2 methylation test: A post hoc analysis in the POBASCAM trial with 14 year follow‐up

LMA De Strooper, J Berkhof… - … journal of cancer, 2018 - Wiley Online Library
DNA methylation analysis of cervical scrapes using FAM19A4 and mir124‐2 genes has
shown a good clinical performance in detecting cervical cancer and advanced CIN lesions …

[HTML][HTML] MCM2 promotes the stemness and sorafenib resistance of hepatocellular carcinoma cells via hippo signaling

X Zhou, J Luo, H Xie, Z Wei, T Li, J Liu, X Liao… - Cell Death …, 2022 - nature.com
Object: A large number of studies have suggested that stemness is an essential mechanism
for drug resistance, metastasis and relapse in hepatocellular carcinoma (HCC). The aim of …

Comparing the performance of FAM19A4 methylation analysis, cytology and HPV16/18 genotyping for the detection of cervical (pre)cancer in high‐risk HPV‐positive …

R Luttmer, LMA De Strooper, J Berkhof… - … journal of cancer, 2016 - Wiley Online Library
Recently, DNA methylation analysis of FAM19A4 in cervical scrapes has been shown to
adequately detect high‐grade cervical intraepithelial neoplasia and cervical cancer (≥ …

CADM1, MAL and miR124-2 methylation analysis in cervical scrapes to detect cervical and endometrial cancer

LMA De Strooper, M van Zummeren… - Journal of clinical …, 2014 - jcp.bmj.com
Aims Gene promoter hypermethylation is recognised as an essential early step in
carcinogenesis, indicating important application areas for DNA methylation analysis in early …