The endoplasmic reticulum (ER) and mitochondria cannot be considered as static structures,
as they intimately communicate, forming very dynamic platforms termed mitochondria …

The rediscovery and reinterpretation of the Warburg effect in the year 2000 occulted for
almost a decade the key functions exerted by mitochondria in cancer cells. Until recent …

Microglia are the main immune cells in the brain and have roles in brain homeostasis and
neurological diseases. Mechanisms underlying microglia–neuron communication remain …

Ferroptosis is a type of iron-dependent regulated cell death caused by the disruption that
occurs when oxidative stress and antioxidant defenses interact, and then driven by lipid …

ABSTRACT Calcium (Ca2+) is a key player in the regulation of many cell functions. Just like
Ca2+, mitochondria are ubiquitous, versatile, and dynamic players in determining both cell …

Background Calcium ions are involved in several human cellular processes including
corticogenesis, transcription, and synaptogenesis. Nevertheless, the relationship between …

Dynamic interactions between organelles are responsible for a variety of intercellular
functions, and the endoplasmic reticulum (ER)–mitochondrial axis is recognized as a …

Repetitive, calcium-mediated contractile activity renders cardiomyocytes critically dependent
on a sustained energy supply and adequate calcium buffering, both of which are provided …

The maintenance of cellular homeostasis involves the participation of multiple organelles.
These organelles are associated in space and time, and either cooperate or antagonize …

Recent studies undoubtedly show the importance of inter organellar connections to maintain
cellular homeostasis. In normal physiological conditions or in the presence of cellular and …