Sažetak Estrogens have long been known as important regulators of the female
reproductive functions; however, our understanding of the role estrogens play in the human …

MicroRNAs (miRNAs) are a class of posttranscriptional regulators that have recently
introduced an additional level of intricacy to our understanding of gene regulation. There are …

In recent years, the highly conserved Lin28 RNA-binding proteins have emerged as factors
that define stemness in several tissue lineages. Lin28 proteins repress let-7 microRNAs and …

Non-coding RNAs (ncRNAs) are regulators of intracellular and intercellular signaling in
breast cancer. ncRNAs modulate intracellular signaling to control diverse cellular processes …

A myriad of physiological processes in mammals are influenced by estrogens and the
estrogen receptors (ERs), ERα and ERβ. As we reviewed previously, given the widespread …

Resistance to anticancer agents is the major clinical obstacle to the successful treatment of
cancer, yet the mechanisms underlying drug resistance have not been fully characterized …

Fulvestrant is a selective estrogen receptor downregulator (SERD) and highly effective
antagonist to hormone-sensitive breast cancers following failure of previous tamoxifen or …

MicroRNAs (miRNAs) are small, single-stranded, endogenous non-coding RNAs that
repress the expression of target genes via post-transcriptional mechanisms. Due to their …

Inflammatory cytokines, especially tumor necrosis factor α (TNF‐α), have been shown to
inhibit osteogenic differentiation of mesenchymal stem cells (MSCs) and bone formation in …

Real-time in situ monitoring of low-abundance cancer biomarkers (eg, miRNAs and
proteins) in living cells by nonenzymatic assembly entirely from original DNA probes …