Tumour budding in solid cancers
Tumour budding is an emerging prognostic biomarker in colorectal cancer (CRC) and other
solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of …
solid cancers. Tumour buds are usually defined as isolated single cancer cells or clusters of …
Chemoresistance in pancreatic cancer
S Zeng, M Pöttler, B Lan, R Grützmann… - International journal of …, 2019 - mdpi.com
Pancreatic ductal adenocarcinoma (PDAC), generally known as pancreatic cancer (PC),
ranks the fourth leading cause of cancer-related deaths in the western world. While the …
ranks the fourth leading cause of cancer-related deaths in the western world. While the …
Genotype tunes pancreatic ductal adenocarcinoma tissue tension to induce matricellular fibrosis and tumor progression
Fibrosis compromises pancreatic ductal carcinoma (PDAC) treatment and contributes to
patient mortality, yet antistromal therapies are controversial. We found that human PDACs …
patient mortality, yet antistromal therapies are controversial. We found that human PDACs …
Tumour microenvironment of pancreatic cancer: immune landscape is dictated by molecular and histopathological features
E Karamitopoulou - British journal of cancer, 2019 - nature.com
Pancreatic cancer is a lethal disease, with fewer than 7% of patients surviving beyond 5
years following diagnosis. Immune responses are known to influence tumour progression …
years following diagnosis. Immune responses are known to influence tumour progression …
Partial EMT in head and neck cancer biology: a spectrum instead of a switch
Our understanding of epithelial-to-mesenchymal transition (EMT) has slowly evolved from a
simple two state, binary model to a multi-step, dynamic continuum of epithelial-to …
simple two state, binary model to a multi-step, dynamic continuum of epithelial-to …
Tumor budding: the name is EMT. Partial EMT.
Tumor budding is a histological phenomenon encountered in various cancers, whereby
individual malignant cells and/or small clusters of malignant cells are seen in the tumor …
individual malignant cells and/or small clusters of malignant cells are seen in the tumor …
Tumor budding in colorectal cancer—ready for diagnostic practice?
VH Koelzer, I Zlobec, A Lugli - Human pathology, 2016 - Elsevier
Tumor budding is an important additional prognostic factor for patients with colorectal cancer
(CRC). Defined as the presence of single tumor cells or small clusters of up to 5 cells in the …
(CRC). Defined as the presence of single tumor cells or small clusters of up to 5 cells in the …
Integrated genomic and immunophenotypic classification of pancreatic cancer reveals three distinct subtypes with prognostic/predictive significance
M Wartenberg, S Cibin, I Zlobec, E Vassella… - Clinical cancer …, 2018 - AACR
Purpose: Current clinical classification of pancreatic ductal adenocarcinoma (PDAC) is
unable to predict prognosis or response to chemo-or immunotherapy and does not take into …
unable to predict prognosis or response to chemo-or immunotherapy and does not take into …
Single-cell RNA-seq reveals the genesis and heterogeneity of tumor microenvironment in pancreatic undifferentiated carcinoma with osteoclast-like giant-cells
X Wang, J Miao, S Wang, R Shen, S Zhang, Y Tian… - Molecular Cancer, 2022 - Springer
Background Undifferentiated carcinoma with osteoclast-like giant cells (OGCs) of pancreas
(UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had …
(UCOGCP) is a rare subtype of pancreatic ductal adenocarcinoma (PDAC), which had …
Tumour budding and its clinical implications in gastrointestinal cancers
Tumour budding in colorectal cancer has become an important prognostic factor.
Represented by single cells or small tumour cell clusters at the invasion front of the tumour …
Represented by single cells or small tumour cell clusters at the invasion front of the tumour …