Botulinum toxin in ophthalmology

JJ Dutton, AM Fowler - Survey of ophthalmology, 2007 - Elsevier
Since its introduction into clinical medicine in 1980, botulinum toxin has become a major
therapeutic drug with applications valuable to many medical sub-specialties. Its use was …

Single‐cell microelectrochemistry

A Schulte, W Schuhmann - Angewandte Chemie International …, 2007 - Wiley Online Library
Needle‐type voltammetric ultramicroelectrodes show exceptional sensitivity for the detection
of redox‐active substances, rapid response times, and total tip diameters in the lower …

Identification of PRRT2 as the causative gene of paroxysmal kinesigenic dyskinesias

JL Wang, L Cao, XH Li, ZM Hu, JD Li, JG Zhang… - Brain, 2011 - academic.oup.com
Paroxysmal kinesigenic dyskinesias is a paroxysmal movement disorder characterized by
recurrent, brief attacks of abnormal involuntary movements induced by sudden voluntary …

What is the role of SNARE proteins in membrane fusion?

JG Duman, JG Forte - American Journal of Physiology-Cell …, 2003 - journals.physiology.org
Soluble N-ethylmaleimide-sensitive factor activating protein receptor (SNARE) proteins have
been at the fore-front of research on biological membrane fusion for some time. The …

Lipid raft association of SNARE proteins regulates exocytosis in PC12 cells

C Salaün, GW Gould, LH Chamberlain - Journal of Biological Chemistry, 2005 - ASBMB
SNAP25 and SNAP23 are plasma membrane SNARE proteins essential for regulated
exocytosis in diverse cell types. Several recent studies have shown that these proteins are …

PRRT2 phenotypes and penetrance of paroxysmal kinesigenic dyskinesia and infantile convulsions

R van Vliet, G Breedveld, J de Rijk-van Andel… - Neurology, 2012 - AAN Enterprises
Objective: To describe the phenotypes and penetrance of paroxysmal kinesigenic
dyskinesia (PKD), a movement disorder characterized by attacks of involuntary movements …

Expression and function of SNAP-25 as a universal SNARE component in GABAergic neurons

LCR Tafoya, M Mameli, T Miyashita… - Journal of …, 2006 - Soc Neuroscience
Intracellular vesicular trafficking and membrane fusion are important processes for nervous
system development and for the function of neural circuits. Synaptosomal-associated protein …

Synaptosomal-associated protein 25 gene expression is hormonally regulated during ovulation and is involved in cytokine/chemokine exocytosis from granulosa cells

M Shimada, Y Yanai, T Okazaki… - Molecular …, 2007 - academic.oup.com
During ovulation, granulosa cells and cumulus cells synthesize and secrete a wide variety of
factors including members of the IL cytokine family via the process of exocytosis. Exocytosis …

A multilevel functional study of a SNAP25 at-risk variant for bipolar disorder and schizophrenia

J Houenou, J Boisgontier, A Henrion… - Journal of …, 2017 - Soc Neuroscience
The synaptosomal-associated protein SNAP25 is a key player in synaptic vesicle docking
and fusion and has been associated with multiple psychiatric conditions, including …

Synaptic biomarker reduction and impaired cognition in the sub-chronic PCP mouse model for schizophrenia

J Gigg, F McEwan, R Smausz, J Neill… - Journal of …, 2020 - journals.sagepub.com
Background: Sub-chronic phencyclidine treatment (scPCP) provides a translational rat
model for cognitive impairments associated with schizophrenia (CIAS). CIAS genetic risk …