Oropharyngeal carcinoma with a special focus on HPV-related squamous cell carcinoma

RL Ferris, W Westra - Annual Review of Pathology: Mechanisms …, 2023 - annualreviews.org
Human papillomavirus–positive oropharyngeal squamous cell carcinoma (HPV-OPSCC)
has one of the most rapidly increasing incidences of any cancer in high-income countries …

[HTML][HTML] Selection of patients for radiotherapy with protons aiming at reduction of side effects: the model-based approach

JA Langendijk, P Lambin, D De Ruysscher… - Radiotherapy and …, 2013 - Elsevier
Most new radiation techniques, have been introduced primarily to reduce the dose to normal
tissues in order to prevent radiation-induced side effects. Radiotherapy with protons is such …

3D radiotherapy dose prediction on head and neck cancer patients with a hierarchically densely connected U-net deep learning architecture

D Nguyen, X Jia, D Sher, MH Lin, Z Iqbal… - Physics in medicine …, 2019 - iopscience.iop.org
The treatment planning process for patients with head and neck (H&N) cancer is regarded
as one of the most complicated due to large target volume, multiple prescription dose levels …

ICRP publication 118: ICRP statement on tissue reactions and early and late effects of radiation in normal tissues and organs–threshold doses for tissue reactions in a …

FA Stewart, AV Akleyev, M Hauer-Jensen, JH Hendry… - Annals of the ICRP, 2012 - Elsevier
This report provides a review of early and late effects of radiation in normal tissues and
organs with respect to radiation protection. It was instigated following a recommendation in …

Evaluation of substantial reduction in elective radiotherapy dose and field in patients with human papillomavirus–associated oropharyngeal carcinoma treated with …

CJ Tsai, SM McBride, N Riaz, JJ Kang… - JAMA …, 2022 - jamanetwork.com
Importance Several de-escalation strategies for human papillomavirus (HPV)–associated
oropharyngeal carcinoma (OPC) have focused on deintensifying gross disease treatment …

Organs at risk radiation dose constraints

G Noël, D Antoni - Cancer/radiothérapie, 2022 - Elsevier
Dose constraints are essential for performing dosimetry, especially for intensity modulation
and for radiotherapy under stereotaxic conditions. We present the update of the …

International guideline on dose prioritization and acceptance criteria in radiation therapy planning for nasopharyngeal carcinoma

AW Lee, WT Ng, JJ Pan, CL Chiang, SS Poh… - International Journal of …, 2019 - Elsevier
Purpose The treatment of nasopharyngeal carcinoma requires high radiation doses. The
balance of the risks of local recurrence owing to inadequate tumor coverage versus the …

Chemo-IMRT of oropharyngeal cancer aiming to reduce dysphagia: swallowing organs late complication probabilities and dosimetric correlates

A Eisbruch, HM Kim, FY Feng, TH Lyden… - International Journal of …, 2011 - Elsevier
PURPOSE: Assess dosimetric correlates of long-term dysphagia after chemo-intensity-
modulated radiotherapy (IMRT) of oropharyngeal cancer (OPC) sparing parts of the …

[PDF][PDF] Tolerance of normal tissue to therapeutic radiation

B Emami - Reports of radiotherapy and Oncology, 2013 - brieflands.com
Radiation therapy is an integral part of the treatment of patients inflicted with cancer. It is
estimated that over 60% of patients with cancer will have radiotherapy as part of their total …

Toxicities affecting quality of life after chemo-IMRT of oropharyngeal cancer: prospective study of patient-reported, observer-rated, and objective outcomes

KU Hunter, M Schipper, FY Feng, T Lyden… - International Journal of …, 2013 - Elsevier
PURPOSE: To test the hypothesis that intensity modulated radiation therapy (IMRT) aiming
to spare the salivary glands and swallowing structures would reduce or eliminate the effects …