Mitochondria are dynamic organelles that continuously undergo fusion/fission to maintain
normal cell physiological activities and energy metabolism. When mitochondrial dynamics is …

Mitochondria are multifaceted and dynamic organelles regulating various important cellular
processes from signal transduction to determining cell fate. As dynamic properties of …

The adverse effects of amorphous silica nanoparticles (SiNPs) exposure on the respiratory
system were increasingly recognized, however, its potential pathogenesis still remains not …

Background Macrophage migration inhibitory factor (MIF) and GTPase dynamin-related
protein 1 (Drp1)-dependent aberrant mitochondrial fission are closely linked to the …

Mitochondria are key metabolic hubs involved in cellular energy production and
biosynthesis. ATP is generated primarily by glucose and fatty acid oxidation through the …

Mitochondria are essential organelles within cells, playing various roles in numerous
cellular processes, including differentiation, growth, apoptosis, energy conversion …

Abstract Silicon dioxide (SiO2)‐induced pulmonary fibrosis is potentially associated with the
impairment of mitochondrial function. Previous research found that inhibition of macrophage …

Abstract Drp1 (Dynamin-Related Protein 1) is a cytoplasmic GTPase protein encoded by the
DNM1L gene that influences mitochondrial dynamics by mediating mitochondrial fission …

Objective Allergic rhinitis (AR) is a common allergic disorder, afflicting thousands of human
beings. Aberrant mitochondrial dynamics are important pathological elements for various …

With the development of lipidomics, the significance of lipid metabolism in various lung
diseases has been noticed recently. Among them, cholesterol metabolism plays a crucial …