Osteoporosis, is the most common bone disorder worldwide characterized by low bone
mineral density, leaving affected bones vulnerable to fracture. Bone homeostasis depends …

Osteoporosis is a common skeletal disease, affecting~ 200 million people around the world.
As a complex disease, osteoporosis is influenced by many factors, including diet (eg calcium …

The bone remodelling cycle (see Poster panel “The bone remodelling cycle”) maintains the
integrity of the skeleton through the balanced activities of its constituent cell types. These are …

Osteoporosis is a common disease with a strong genetic component characterized by
reduced bone mass, defects in the microarchitecture of bone tissue, and an increased risk of …

For more than a decade, Wnt signaling pathways have been the focus of intense research
activity in bone biology laboratories because of their importance in skeletal development …

Osteoporosis and fracture risk are common complex diseases, caused by an interaction of
numerous disease susceptibility genes and environmental factors. With the advances in …

Osteoporosis and periodontitis are both diseases characterized by bone resorption.
Osteoporosis features systemic degenerative bone loss that leads to loss of skeletal …

Background Osteoporosis is diagnosed by the measurement of bone mineral density, which
is a highly heritable and multifactorial trait. We aimed to identify genetic loci that are …

Background Bone mineral density influences the risk of osteoporosis later in life and is
useful in the evaluation of the risk of fracture. We aimed to identify sequence variants …

We aimed to identify genetic variants associated with cortical bone thickness (CBT) and
bone mineral density (BMD) by performing two separate genome-wide association study …