Recent advances in antiviral activities of triterpenoids

Y Liu, L Yang, H Wang, Y Xiong - Pharmaceuticals, 2022 - mdpi.com
Triterpenoids, important secondary plant metabolites made up of six isoprene units, are
found widely in higher plants and are studied for their structural variety and wide range of …

Ziziphus jujuba Mill., a plant used as medicinal food: a review of its phytochemistry, pharmacology, quality control and future research

SJ Liu, YP Lv, ZS Tang, Y Zhang, HB Xu… - Phytochemistry …, 2021 - Springer
Abstract Jujubae Fructus (ZJF)[called Dazao (大枣) in Chinese], the fruit of Ziziphus jujuba
Mill.(ZJ), is utilized as a food and traditional medicine in China. In TCM use, ZJF is …

Virtual screening of Indonesian herbal compounds as COVID-19 supportive therapy: machine learning and pharmacophore modeling approaches

L Erlina, RI Paramita, WA Kusuma, F Fadilah… - … Medicine and Therapies, 2022 - Springer
Background The number of COVID-19 cases continues to grow in Indonesia. This
phenomenon motivates researchers to find alternative drugs that function for prevention or …

The host protease KLK5 primes and activates spike proteins to promote human betacoronavirus replication and lung inflammation

H Kim, Y Kang, S Kim, D Park, SY Heo, JS Yoo… - Science …, 2024 - science.org
Coronaviruses rely on host proteases to activate the viral spike protein, which facilitates
fusion with the host cell membrane and the release of viral genomic RNAs into the host cell …

Isolation of amaranthin synthetase from Chenopodium quinoa and construction of an amaranthin production system using suspension‐cultured tobacco BY‐2 cells

T Imamura, N Isozumi, Y Higashimura… - Plant Biotechnology …, 2019 - Wiley Online Library
Betalains are plant pigments primarily produced by plants of the order Caryophyllales.
Because betalain possesses anti‐inflammatory and anticancer activities, it may be useful as …

Ursonic acid from medicinal herbs inhibits PRRSV replication through activation of the innate immune response by targeting the phosphatase PTPN1

Y Yang, Y Gao, H Sun, J Bai, J Zhang, L Zhang… - Veterinary …, 2024 - Springer
Porcine reproductive and respiratory syndrome (PRRS), caused by the PRRS virus
(PRRSV), has caused substantial economic losses to the global swine industry due to the …

Using hierarchical virtual screening to combat drug resistance of the HIV-1 protease

N Li, RI Ainsworth, B Ding, T Hou… - Journal of chemical …, 2015 - ACS Publications
Human immunodeficiency virus (HIV) protease inhibitors (PIs) are important components of
highly active anti-retroviral therapy (HAART) that block the catalytic site of HIV protease, thus …

[HTML][HTML] Theoretical model for the design and preparation of a CNT–ursonic acid drug matrix as HIV-gp120 entry inhibitor

DU Zuru - Scientific African, 2019 - Elsevier
Abstract Human Immunodeficiency Virus (HIV) which infection results into Acquired
Immunodeficiency Syndrome (AIDS) has claimed the lives of one half of its 70 million …

[HTML][HTML] Exposing the molecular screening method of Indonesian natural products derivate as drug candidates for cervical cancer

USF Tambunan, AA Parikesit… - Iranian journal of …, 2017 - ncbi.nlm.nih.gov
The menace of cervical cancer has reached an alarming rate. There are more than 450.000
cases of cervical cancer yearly, with mortality rate of about 50%. This deadly cancer is …

[图书][B] Kimia medisinal: dasar-dasar dalam perancangan obat

PD Muchtaridi - 2018 - books.google.com
Penemuan obat baru tidak lepas dari peran ilmu kimia medisinal, maka sewajarnya jika
calon sarjana, master, dan doktor farmasi memahami dan mengerti tentang kimia medisinal …