RNA binding proteins (RBPs) regulate all aspects in the life cycle of RNA molecules. To
elucidate the elements that guide RNA specificity, regulatory mechanisms, and functions of …

Alternative splicing of mRNA precursors provides an important means of genetic control and
is a crucial step in the expression of most genes. Alternative splicing markedly affects human …

Abstract The role of Fat Mass and Obesity-associated protein (FTO) and its substrate N6-
methyladenosine (m 6 A) in mRNA processing and adipogenesis remains largely unknown …

Splicing factor SRSF1 is upregulated in human breast tumors, and its overexpression
promotes transformation of mammary cells. Using RNA-seq, we identified SRSF1-regulated …

Serine and arginine-rich (SR) proteins are RNA-binding proteins (RBPs) known as
constitutive and alternative splicing regulators. As splicing is linked to transcriptional and …

Nuclear export factor 1 (NXF1) exports mRNA to the cytoplasm after recruitment to mRNA by
specific adaptor proteins. How and why cells use numerous different export adaptors is …

The SR protein family comprises a number of phylogenetically conserved and structurally
related proteins with a characteristic domain rich in arginine and serine residues, known as …

Metazoan genomes encode hundreds of RNA-binding proteins (RBPs) but RNA-binding
preferences for relatively few RBPs have been well defined. Current techniques for …

SR proteins are well-characterized RNA binding proteins that promote exon inclusion by
binding to exonic splicing enhancers (ESEs). However, it has been unclear whether …

The study of gene regulation in cells has recently begun to shift from a period dominated by
the study of transcription factor‐DNA interactions to a new focus on RNA regulation. This …