[HTML][HTML] Tendon injury and repair–A perspective on the basic mechanisms of tendon disease and future clinical therapy

JG Snedeker, J Foolen - Acta biomaterialia, 2017 - Elsevier
Tendon is an intricately organized connective tissue that efficiently transfers muscle force to
the bony skeleton. Its structure, function, and physiology reflect the extreme, repetitive …

Tendons–time to revisit inflammation

JD Rees, M Stride, A Scott - British journal of sports medicine, 2014 - bjsm.bmj.com
It is currently widely accepted among clinicians that chronic tendinopathy is caused by a
degenerative process devoid of inflammation. Current treatment strategies are focused on …

[HTML][HTML] Current opinions on tendinopathy

JF Kaux, B Forthomme, C Le Goff… - Journal of sports …, 2011 - ncbi.nlm.nih.gov
Tendinopathy is characterized by pain in the tendon and impaired performance sometimes
associated with swelling of the tendon. Its diagnosis is usually clinical but ultrasonography …

The past, present and future in scaffold-based tendon treatments

AJ Lomas, CNM Ryan, A Sorushanova… - Advanced drug delivery …, 2015 - Elsevier
Tendon injuries represent a significant clinical burden on healthcare systems worldwide. As
the human population ages and the life expectancy increases, tendon injuries will become …

Inflammation in tendinopathy

A D'Addona, N Maffulli, S Formisano, D Rosa - The Surgeon, 2017 - Elsevier
Pain and functional limitation are frequent in symptomatic tendinopathy. The essential lesion
of tendinopathy is a failed healing response. Understanding the cellular and molecular …

Enhancement of tenogenic differentiation of human adipose stem cells by tendon-derived extracellular matrix

G Yang, BB Rothrauff, H Lin, R Gottardi, PG Alexander… - Biomaterials, 2013 - Elsevier
Mesenchymal stem cells (MSCs) have gained increasing research interest for their potential
in improving healing and regeneration of injured tendon tissues. Developing functional three …

Genetic influences in sport and physical performance

Z Puthucheary, JRA Skipworth, J Rawal, M Loosemore… - Sports medicine, 2011 - Springer
The common inheritance of approximately 20 000 genes defines each of us as human.
However, substantial variation exists between individual human genomes, including …

[HTML][HTML] The Achilles tendon: fundamental properties and mechanisms governing healing

BR Freedman, JA Gordon… - Muscles, ligaments and …, 2014 - ncbi.nlm.nih.gov
This review highlights recent research on Achilles tendon healing, and comments on the
current clinical controversy surrounding the diagnosis and treatment of injury. The processes …

What are the validated animal models for tendinopathy?

PPY Lui, N Maffulli, C Rolf… - Scandinavian journal of …, 2011 - Wiley Online Library
Chronic tendinopathy refers to a broad spectrum of pathological conditions in tendons and
their insertion, with symptoms including activity‐related chronic pain. To study the …

The effect of matrix metalloproteinase inhibition on tendon-to-bone healing in a rotator cuff repair model

A Bedi, D Kovacevic, C Hettrich, LV Gulotta… - Journal of shoulder and …, 2010 - Elsevier
HYPOTHESIS: Recent studies have demonstrated a potentially critical role of matrix
metalloproteinases (MMPs) and tissue inhibitors of matrix metalloproteinases (TIMPs) in the …