Simple Summary REV7 is a multifunctional protein involved in various biological processes
including DNA damage response and mutagenesis, cell cycle regulation, primordial germ …

Background: REV1 is a member of the translesion synthesis DNA polymerase Y family. It is
an essential player in a variety of DNA replication activities, and perform major roles in the …

REV7 is a multifunctional protein implicated in various biological processes, including DNA
damage response. REV7 expression in human cancer cells affects their sensitivity to DNA …

Background REV7 is a multifunctional protein involved in various biological processes,
including DNA damage response. REV7 expression in human cancer cells influences …

MAD2L2 is a small HORMA domain protein that plays a crucial role in DNA repair and
mitosis. In both TLS and shieldin, the dimerization of MAD2L2 via its HORMA domain is …

Cohesin mediates the 3-D structure of chromatin and is involved in maintaining genome
stability and function. The cohesin core comprises Smc1 and Smc3, elongated-shaped …

REV7 is a multifunctional protein essential for promoting cellular tolerance to DNA damage.
REV7 expression is associated with disease progression and prognosis in several human …

Cancer is a group of diseases characterized by uncontrolled growth and spread of cells.
Cancer develops from normal cells by comprising multiple changes on a molecular level …

DNA repair and cell cycle regulation are potential biological fields to develop molecular
targeting therapies for cancer. Human REV7 was originally discovered as a homologous …