Gammaherpesviruses are lymphotropic viruses that are associated with the development of
lymphoproliferative diseases, lymphomas, as well as other nonlymphoid cancers. Most …

Immediately after entry into host cells, viruses are sensed by the innate immune system,
leading to the activation of innate antiviral effector mechanisms including the type I interferon …

Innate immune responses are crucial for limiting virus infection. However, viruses often
hijack our best defenses for viral objectives. Human Cytomegalovirus (HCMV) is a beta …

Alpha/beta interferon (IFN-α/β) protects the host from virus infection by inhibition of lytic virus
replication in infected cells and modulation of the antiviral cell-mediated immune response …

To clarify the function (s) of the herpes simplex virus 1 (HSV-1) major virion structural protein
UL47 (also designated VP13/14), we screened cells overexpressing UL47 for UL47-binding …

We have investigated the role of signal transducer and activator of transcription (STAT) 2
during human cytomegalovirus (HCMV) replication and found that protein levels of STAT2 …

Abstract Porcine circovirus 2 (PCV2) has been proved to increase the risk of other
pathogens infection through antagonizing the host type I interferon (IFN) response …

Cancers associated with the oncogenic gammaherpesviruses, Epstein-Barr virus and
Kaposi sarcoma herpesvirus, are notable for their constitutive activation of the transcription …

Rationale: Idiopathic pulmonary fibrosis (IPF) is a chronic progressive fibrotic lung disorder
of unknown cause. Several studies suggest an association between Epstein-Barr virus …

Virus‐infection of mammalian cells causes transcriptional induction of many cellular genes,
collectively called as “viral stress‐inducible genes.” The proteins encoded by these genes …