The increasing prevalence of diabetes and its complications, such as cardiovascular and
kidney disease, remains a huge burden globally. Identification of biomarkers for the …

Although diabetic kidney disease (DKD) remains the leading cause of end-stage kidney
disease eventually requiring chronic kidney replacement therapy, the prevalence of DKD …

Intestinal microbiota-derived metabolites have biological importance for the host.
Polyamines, such as putrescine and spermidine, are produced by the intestinal microbiota …

Chronic kidney disease (CKD) remains a major epidemiological, clinical, and biomedical
challenge. During CKD, renal tubular epithelial cells (TECs) present a persistent …

Chronic kidney disease (CKD) has a high prevalence in the general population and is
associated with high mortality; a need therefore exists for better biomarkers for diagnosis …

The involvement of host immunity in the gut microbiota-mediated colonization resistance to
Clostridioides difficile infection (CDI) is incompletely understood. Here, we show that …

Metabolomics is a rapidly advancing field, and much of our understanding of the subject has
come from research on cell lines. However, the results and interpretation of such studies …

Diabetic kidney disease (DKD) remains one of the leading causes of reduced lifespan in
diabetes. The quest for both prognostic and surrogate endpoint biomarkers for advanced …

Diabetic kidney disease (DKD) is one of the most prevalent comorbidities of diabetes
mellitus and the leading cause of the end‐stage renal disease (ESRD). DKD results from …

The high susceptibility of neonates to infections has been assumed to be due to immaturity
of the immune system, but the mechanism remains unclear. By colonizing adult germ-free …