In response to rapidly growing rates of comorbidity among psychiatric disorders, clinical
scientists have become interested in identifying transdiagnostic processes that can help …

Adolescence is a time in development when significant changes occur in affective
neurobiology. These changes provide a prolonged period of plasticity to prepare the …

Purpose of Review PTSD in youth is common and debilitating. In contrast to adult PTSD,
relatively little is known about the neurobiology of pediatric PTSD, nor how …

Early adverse environmental exposures during brain development are widespread risk
factors for the onset of severe mental disorders and strong and consistent predictors of …

Mature amygdala-prefrontal circuitry regulates affect in adulthood but shows protracted
development. In altricial and semialtricial species, caregivers provide potent affect regulation …

Early experiences critically shape the structure and function of the brain. Perturbations in
typical/species-expected early experiences are known to have profound neural effects …

Highlights•Emotion regulation serves to modify the nature, intensity or duration of
emotions.•Prefrontal cortex may modulate subcortical structures when regulating …

Species-expected caregiving early in life is critical for the normative development and
regulation of emotional behavior, the ability to effectively evaluate affective stimuli in the …

Early adverse experiences are associated with heighted vulnerability for stress-related
psychopathology across the lifespan. While extensive work has investigated the effects of …

Abstract As highlighted by Eisenberg, Cumberland, and Spinrad (1998), parents play a
critical role in children's socioemotional development, in part, by shaping how children and …