Molecular characteristics of RAGE and advances in small-molecule inhibitors

HJ Kim, MS Jeong, SB Jang - International journal of molecular sciences, 2021 - mdpi.com
Receptor for advanced glycation end-products (RAGE) is a member of the immunoglobulin
superfamily. RAGE binds and mediates cellular responses to a range of DAMPs (damage …

Dietary fructose and the metabolic syndrome

A Miller, K Adeli - Current opinion in gastroenterology, 2008 - journals.lww.com
There is much evidence from both animal models and human studies supporting the notion
that fructose is a highly lipogenic nutrient that, when consumed in high quantities …

Soluble forms of RAGE in human diseases: clinical and therapeutical implications

F Santilli, N Vazzana, LG Bucciarelli… - Current medicinal …, 2009 - ingentaconnect.com
The ligand-receptor for advanced glycation end-products (RAGE) axis has emerged as a
novel pathway involved in a wide spectrum of diseases, including diabetes mellitus …

Soluble forms of RAGE in internal medicine

N Vazzana, F Santilli, C Cuccurullo, G Davì - Internal and emergency …, 2009 - Springer
The receptor for advanced glycation end-products (RAGE) and its ligands are intimately
involved in the pathobiology of a wide range of diseases that share common features, such …

Pathological Implications of Receptor for Advanced Glycation End‐Product (AGER) Gene Polymorphism

M Serveaux-Dancer, M Jabaudon, I Creveaux… - Disease …, 2019 - Wiley Online Library
The receptor for advanced glycation end‐products (RAGE) is a cell surface transmembrane
multiligand receptor, encoded by the AGER gene. RAGE presents many transcripts, is …

The AGE-RAGE Axis and the Pathophysiology of Multimorbidity in COPD

NL Reynaert, LEGW Vanfleteren… - Journal of Clinical …, 2023 - mdpi.com
Chronic obstructive pulmonary disease (COPD) is a disease of the airways and lungs due to
an enhanced inflammatory response, commonly caused by cigarette smoking. Patients with …

The role of HMGB1-RAGE axis in migration and invasion of hepatocellular carcinoma cell lines

RC Chen, PP Yi, RR Zhou, MF Xiao, ZB Huang… - Molecular and cellular …, 2014 - Springer
High mobility group protein box1 (HMGB1) and its receptor—receptor for advanced
glycation end products (RAGE) are pivotal factors in the development and progression of …

The role of soluble receptor for advanced glycation end-products (sRAGE) in the general population and patients with diabetes mellitus with a focus on renal function …

M Steenbeke, S De Bruyne, M De Buyzere… - Critical Reviews in …, 2021 - Taylor & Francis
Isoforms of the receptor for advanced glycation end-product (RAGE) protein, which lack the
transmembrane and the signaling (soluble RAGE or sRAGE) domains are hypothesized to …

RAGE-mediated cell signaling

A Rouhiainen, J Kuja-Panula, S Tumova… - Calcium-binding proteins …, 2013 - Springer
RAGE (receptor for advanced glycation end products) is a multi-ligand receptor that belongs
to the immunoglobulin superfamily of transmembrane proteins. RAGE binds AGEs …

Receptor for Advanced Glycation Endproducts (RAGE): a formidable force in the pathogenesis of the cardiovascular complications of diabetes & aging

R Ramasamy, SF Yan, V D'Agati… - Current molecular …, 2007 - ingentaconnect.com
Unifying mechanisms for the consequences of aging and chronic diabetes are coming to
light with the identification that common to both settings is the production and accumulation …