Oxidative protein folding in the intermembrane space of human mitochondria

C Zarges, J Riemer - FEBS Open Bio, 2024 - Wiley Online Library
The mitochondrial intermembrane space hosts a machinery for oxidative protein folding, the
mitochondrial disulfide relay. This machinery imports a large number of soluble proteins into …

Recent advances in microbial synthesis of free heme

S Yang, Z Guo, J Sun, J Wei, Q Ma, X Gao - Applied Microbiology and …, 2024 - Springer
Heme is an iron-containing porphyrin compound widely used in the fields of healthcare,
food, and medicine. Compared to animal blood extraction, it is more advantageous to …

Cryo-EM of CcsBA reveals the basis for cytochrome c biogenesis and heme transport

DL Mendez, EP Lowder, DE Tillman… - Nature chemical …, 2022 - nature.com
Although the individual structures and respiratory functions of cytochromes are well studied,
the structural basis for their assembly, including transport of heme for attachment, are …

Helicobacter pylori and Campylobacter jejuni bacterial holocytochrome c synthase structure-function analysis reveals conservation of heme binding

T Yeasmin, SC Carroll, DJ Hawtof… - Communications …, 2024 - nature.com
Heme trafficking is essential for cellular function, yet mechanisms of transport and/or heme
interaction are not well defined. The System I and System II bacterial cytochrome c …

[HTML][HTML] (Re)-definition of the holo-and apo-Fur direct regulons of Helicobacter pylori

A Vannini, E Pinatel, PE Costantini, S Pelliciari… - Journal of Molecular …, 2024 - Elsevier
Iron homeostasis is a critical process for living organisms because this metal is an essential
co-factor for fundamental biochemical activities, like energy production and detoxification …

Genome-Scale Mining of Acetogens of the Genus Clostridium Unveils Distinctive Traits in [FeFe]- and [NiFe]-Hydrogenase Content and Maturation

PF Di Leonardo, G Antonicelli, V Agostino… - Microbiology …, 2022 - Am Soc Microbiol
Knowledge of the organizational and functional properties of hydrogen metabolism is pivotal
to the construction of a framework supportive of a hydrogen-fueled low-carbon economy …

Biogenesis of cytochromes c and c1 in the electron transport chain of malaria parasites

AE García-Guerrero, RG Marvin, AM Blackwell… - bioRxiv, 2024 - biorxiv.org
Plasmodium malaria parasites retain an essential mitochondrional electron transport chain
(ETC) that is critical for growth within humans and mosquitoes and a key antimalarial drug …

Investigation of the Molecular Mechanisms of the Eukaryotic Cytochrome-c Maturation System

AV Silva, MO Firmino, NL Costa, RO Louro… - Biomolecules, 2022 - mdpi.com
Cytochromes-c are ubiquitous heme proteins with enormous impact at the cellular level,
being key players in metabolic processes such as electron transfer chains and apoptosis …

Prospective antibacterial inhibition of c-type cytochrome synthesis

J Pessoa - Trends in Molecular Medicine, 2021 - cell.com
Sutherland et al. recently reported the in vitro inhibition of Helicobacter hepaticus
cytochrome c (cyt c) synthase, which may inactivate c-type cytochromes in this and in other …

Exploring Processes to Improve Electroactivity in Shewanella Oneidensis Mr-1: Understanding Biofilm Formation and Cytochrome C Maturation

AV Silva - 2023 - search.proquest.com
Bioelectrochemical systems (BES) are a highly sustainable and versatile platform for
electricity production, wastewater treatment, environmental bioremediation …