Psychedelics

DE Nichols - Pharmacological reviews, 2016 - ASPET
Psychedelics (serotonergic hallucinogens) are powerful psychoactive substances that alter
perception and mood and affect numerous cognitive processes. They are generally …

[HTML][HTML] Activity-dependent plasticity in spinal cord injury

JV Lynskey, A Belanger, R Jung - Journal of rehabilitation research …, 2008 - ncbi.nlm.nih.gov
The adult mammalian central nervous system (CNS) is capable of considerable plasticity,
both in health and disease. After spinal neurotrauma, the degrees and extent of …

Activity-dependent increase in neurotrophic factors is associated with an enhanced modulation of spinal reflexes after spinal cord injury

MP Côté, GA Azzam, MA Lemay, V Zhukareva… - Journal of …, 2011 - liebertpub.com
Activity-based therapies such as passive bicycling and step-training on a treadmill contribute
to motor recovery after spinal cord injury (SCI), leading to a greater number of steps …

Stiff person syndrome-associated autoantibodies to amphiphysin mediate reduced GABAergic inhibition

C Geis, A Weishaupt, S Hallermann, B Grünewald… - Brain, 2010 - academic.oup.com
Synaptic inhibition is a central factor in the fine tuning of neuronal activity in the central
nervous system. Symptoms consistent with reduced inhibition such as stiffness, spasms and …

Plasticity of spinal cord reflexes after a complete transection in adult rats: relationship to stepping ability

I Lavrov, YP Gerasimenko… - Journal of …, 2006 - journals.physiology.org
Changes in epidurally induced (S1) spinal cord reflexes were studied as a function of the
level of restoration of stepping ability after spinal cord transection (ST). Three types of …

A novel experimental model of cervical spondylotic myelopathy (CSM) to facilitate translational research

SK Karadimas, ES Moon, WR Yu… - Neurobiology of …, 2013 - Elsevier
Cervical spondylotic myelopathy (CSM) is the most common form of spinal cord impairment
in adults. However critical gaps in our knowledge of the pathobiology of this disease have …

BDNF induced by treadmill training contributes to the suppression of spasticity and allodynia after spinal cord injury via upregulation of KCC2

S Tashiro, M Shinozaki, M Mukaino… - … and neural repair, 2015 - journals.sagepub.com
Background. Spasticity and allodynia are major sequelae that affect the quality of life and
daily activities of spinal cord injury (SCI) patients. Although rehabilitation ameliorates …

Spasticity predicts motor recovery for patients with subacute motor complete spinal cord injury

S Sangari, B Chen, F Grover, H Salsabili… - Annals of …, 2024 - Wiley Online Library
Objective A motor complete spinal cord injury (SCI) results in the loss of voluntary motor
control below the point of injury. Some of these patients can regain partial motor function …

Functional plasticity following spinal cord lesions

A Frigon, S Rossignol - Progress in brain research, 2006 - Elsevier
Spinal cord injury results in marked modification and reorganization of several reflex
pathways caudal to the injury. The sudden loss or disruption of descending input engenders …

Adeno-associated virus-mediated L1 expression promotes functional recovery after spinal cord injury

J Chen, J Wu, I Apostolova, M Skup, A Irintchev… - Brain, 2007 - academic.oup.com
Paucity of permissive molecules and abundance of inhibitory molecules in the injured spinal
cord of adult mammals prevent axons from successful regeneration and, thus, contribute to …