Cancer remains a serious threat to human health owing to the lack of effective treatments.
Photodynamic therapy (PDT) has emerged as a promising non-invasive cancer treatment …

Abstract Poly (α-l-lysine)(PLL) is a class of water-soluble, cationic biopolymer composed of α-
l-lysine structural units. The previous decade witnessed tremendous progress in the …

Molecular theranostic platforms with precise molecular structure and multiple functions hold
great promise for cancer therapy. Different from the current strategy to incorporate various …

Significant advances in physicochemical properties of polymeric micelles enable
optimization of therapeutic drug efficacy, supporting nanomedicine manufacturing and …

With rapid emergence of multi-drug resistant microbes, it is imperative to seek alternative
means for infection control. Optical waveguides are an auspicious delivery method for …

Bone metastasis is one of the leading causes of cancer-related death and remains incurable
in spite of great efforts. Bone-targeted nanoparticle-based drug carriers can overcome the …

Clinically approved doxorubicin (Dox)-loaded liposomes (eg, Doxil) guarantee good
biosafety, but their insufficient nuclear delivery of Dox (< 0.4%) after cellular uptake …

The emergence of multidrug resistance (MDR) in malignant tumors is the primary reason for
invalid chemotherapy. Antitumor drugs are often adversely affected by the MDR of tumor …

Multidrug resistance (MDR) of tumors is one of the clinical direct reasons for chemotherapy
failure. MDR directly leads to tumor recurrence and metastasis, with extremely grievous …

Purpose The objective of this study was to develop long-circulating solid lipid nanoparticles
(LSLN) containing a novel curcumin (CU) derivative (CU1), to improve CU1ʹs …