European LeukemiaNet 2020 recommendations for treating chronic myeloid leukemia

A Hochhaus, M Baccarani, RT Silver, C Schiffer… - Leukemia, 2020 - nature.com
The therapeutic landscape of chronic myeloid leukemia (CML) has profoundly changed over
the past 7 years. Most patients with chronic phase (CP) now have a normal life expectancy …

[HTML][HTML] Chronic myeloid leukemia in 2020

R Hehlmann - Hemasphere, 2020 - journals.lww.com
New insights have emerged from maturing long-term academic and commercial clinical
trials regarding optimum management of chronic myeloid leukemia (CML). Velocity of …

Guidelines for the treatment of chronic myeloid leukemia from the NCCN and ELN: differences and similarities

Z Narlı Özdemir, NA Kılıçaslan, M Yılmaz… - International journal of …, 2023 - Springer
Patients diagnosed with chronic myeloid leukemia (CML) in chronic phase can now have a
life expectancy comparable to that of the general population thanks to the use of tyrosine …

Current evidence on the efficacy and safety of generic imatinib in CML and the impact of generics on health care costs

A Erçalışkan, D Seyhan Erdoğan… - Blood advances, 2021 - ashpublications.org
Since the introduction of imatinib, the management of chronic myeloid leukemia (CML) has
changed considerably. Tyrosine kinase inhibitors (TKIs) are the mainstay of CML treatment; …

Efficacy and safety of generic imatinib after switching from original imatinib in patients treated for chronic myeloid leukemia in the United States

I Abou Dalle, H Kantarjian, J Burger, Z Estrov… - Cancer …, 2019 - Wiley Online Library
Introduction Imatinib is standard therapy for patients with chronic myeloid leukemia (CML). In
February 2016, a generic formulation entered the US market. Physicians and patients are …

Moving on from 2013 to 2020 European LeukemiaNet recommendations for treating chronic myeloid leukemia: what has changed over the 7 years?

U Yilmaz, AE Eskazan - Expert review of hematology, 2020 - Taylor & Francis
In order to harmonize and standardize the management of patients with chronic myeloid
leukemia (CML), the European LeukemiaNet (ELN) produced recommendations in the …

Treatment-Free Remission—A New Aim in the Treatment of Chronic Myeloid Leukemia

P Kwaśnik, K Giannopoulos - Journal of Personalized Medicine, 2021 - mdpi.com
Tyrosine kinases inhibitors (TKIs) revolutionized chronic myeloid leukemia (CML) treatment
for many years, prolonging patients' life expectancy to be comparable to age-matched …

A safety review of tyrosine kinase inhibitors for chronic myeloid leukemia

D Özmen, DD Alpaydın, MA Saldoğan… - Expert Opinion on …, 2024 - Taylor & Francis
Introduction Since the introduction of first tyrosine kinase inhibitor (TKI) imatinib, the
treatment of chronic myeloid leukemia (CML) has reached excellent survival expectancies …

Efficacy and safety profile of generic imatinib in patients with newly diagnosed chronic myeloid leukemia-chronic phase: sharing experience of a hemato-oncology …

A Phukan, PK Mandal, TK Dolai - Annals of Hematology, 2021 - Springer
In India, CML is the commonest adult leukemia. Imatinib is the gold standard for frontline
treatment of newly diagnosed CML-CP patients. The present study was conducted to assess …

Safety and efficacy of switching from branded to generic imatinib in chronic phase chronic myeloid leukemia patients treated in Italy

M Bonifacio, L Scaffidi, G Binotto, MC Miggiano… - Leukemia Research, 2018 - Elsevier
The use of generic drugs after patent expiration of their originators is a relative novelty in the
treatment of chronic cancer patients in Western countries. In this observational study we …