CH‐Functionalization of Heterocycles with the Formation of C− O, C− N, C− S/Se, and C− P Bonds by Intermolecular Addition of Heteroatom‐Centered Radicals

AS Budnikov, IB Krylov, OM Mulina… - Advanced Synthesis …, 2023 - Wiley Online Library
In the last decade, free radicals have found a wide application in functionalization of
unsaturated compounds, such as alkenes, alkynes, and arenes, via the free‐radical addition …

External electrolyte-free electrochemical one-pot cascade synthesis of 4-thiocyanato-1H-pyrazoles

WB He, SJ Zhao, JY Chen, J Jiang, X Chen, X Xu… - Chinese Chemical …, 2023 - Elsevier
ABSTRACT A practical synthetic method for 4-thiocyanato-1H-pyrazoles through the
electrochemical cascade reaction of hydrazines, 1, 3-diones and NH 4 SCN under metal …

Photocatalytic C–H Thiocyanation of NH2-Enaminones and the Tunable Synthetic Routes to 2-Aminothiazoles and 2-Thiazolinones

J Zeng, JP Wan, Y Liu - The Journal of Organic Chemistry, 2022 - ACS Publications
Visible light photocatalytic reactions of NH2-enaminones and ammonium thiocyanate for
chemoselective α-C–H thiocyanation have been realized for the first time, providing a …

[HTML][HTML] Electrooxidation is a promising approach to functionalization of pyrazole-type compounds

BV Lyalin, VL Sigacheva, AS Kudinova, SV Neverov… - Molecules, 2021 - mdpi.com
The review summarizes for the first time the poorly studied electrooxidative functionalization
of pyrazole derivatives leading to the C–Cl, C–Br, C–I, C–S and N–N coupling products with …

Visible Light-Mediated C(sp2)–H Selenylation of Amino Pyrazole and Amino Uracils in the Presence of Rose Bengal as an Organophotocatalyst

D Ali, T Parvin, LH Choudhury - The Journal of Organic Chemistry, 2022 - ACS Publications
Herein, we report an efficient methodology for the synthesis of alkyl, benzyl, and phenyl
selenoethers of aminopyrazoles and aminouracils by C (sp2)–H functionalization in the …

Metal-free C (sp2)-H perfluoroalkylsulfonylation and configuration inversion: Stereoselective synthesis of α-perfluoroalkylsulfonyl E-enaminones

Q Yu, Y Liu, JP Wan - Chinese Chemical Letters, 2021 - Elsevier
Abstract The perfluoroalkylsulfonylation (CF 3 SO 2, C 2 F 5 SO 2 and CHF 2 SO 2) in the
enaminone C single bondH bonds has been developed simply via the promotion of …

Iodine-catalyzed multicomponent synthesis of highly fluorescent pyrimidine-linked imidazopyridines

SS Acharya, P Bhaumick, R Kumar, LH Choudhury - ACS omega, 2022 - ACS Publications
Herein, we report a metal-free one-pot three-component reaction of aryl methyl ketones, 2-
aminopyridines, and barbituric acids for the synthesis of pyrimidine-linked imidazopyridines …

Transition Metal-Free C—H Thiocyanation and Selenocyanation Based on Thermochemical, Photocatalytic and Electrochemical Process

X Zhongrong, W Jieping, L Yunyun - Chinese Journal of Organic …, 2023 - sioc-journal.cn
Thiocyano and selenocyano are both important functional groups with broad application in
organic synthesis. Such functional structures also occur frequently in molecules possessing …

Electrochemical oxidative regio-and stereo-selective thio (seleno) cyanation of enamides and mechanistic insights

Q Gu, Z Cheng, X Xiong, B Xiong, Y Zhao, HD Xu… - Green …, 2022 - pubs.rsc.org
An electrochemical oxidative regio-and stereo-selective thio (seleno) cyanation of enamides
has been developed to access (E)-β-thio (seleno) cyanated enamide compounds under …

Water Microdroplet Chemistry for Accelerating Green Thiocyanation and Discovering Water-Controlled Divergence

L Xue, B Zheng, J Sun, J Liu… - … Sustainable Chemistry & …, 2023 - ACS Publications
As an important class of five-membered N-heterocyclic compounds, pyrazolin-5-one
derivatives play an extremely important role in the construction of fine chemicals and …