Statins: Adverse reactions, oxidative stress and metabolic interactions

A Liu, Q Wu, J Guo, I Ares, JL Rodríguez… - Pharmacology & …, 2019 - Elsevier
Abstract Statins, 3-hydroxy-3-methylglutaryl-coenzyme A reductase inhibitors, are currently
the most effective lipid-lowering drugs, effectively reducing the plasma total cholesterol and …

[HTML][HTML] Antioxidants in liver health

S Casas-Grajales, P Muriel - World journal of gastrointestinal …, 2015 - ncbi.nlm.nih.gov
Liver diseases are a worldwide medical problem because the liver is the principal
detoxifying organ and maintains metabolic homeostasis. The liver metabolizes various …

Progress of research on the role of active ingredients of Citri Reticulatae Pericarpium in liver injury

S Gao, X Chen, Z Yu, R Du, B Chen, Y Wang, X Cai… - Phytomedicine, 2023 - Elsevier
Background Liver is a vital organ responsible for metabolizing and detoxifying both
endogenous and exogenous substances in the body. However, it is susceptible to damage …

A recent review of citrus flavanone naringenin on metabolic diseases and its potential sources for high yield-production

N Karim, Z Jia, X Zheng, S Cui, W Chen - Trends in Food Science & …, 2018 - Elsevier
Background Metabolic syndromes are the multi-metabolic abnormality characterized by
hyperlipidemia, obesity, hyperglycemia, diabetes, hypertension, cardiovascular disease …

A comprehensive overview of hepatoprotective natural compounds: mechanism of action and clinical perspectives

R Domitrović, I Potočnjak - Archives of toxicology, 2016 - Springer
Hepatoprotective effects of natural compounds have been frequently attributed to their
antioxidant properties and the ability to mobilize endogenous antioxidant defense system …

[HTML][HTML] A comprehensive systematic review of the effects of naringenin, a citrus-derived flavonoid, on risk factors for nonalcoholic fatty liver disease

F Naeini, Z Namkhah, A Ostadrahimi, H Tutunchi… - Advances in …, 2021 - Elsevier
Nonalcoholic fatty liver disease (NAFLD) has become the most common cause of liver
dysfunction worldwide. Recently, some natural compounds have attracted growing interest …

Quantitative analysis of rutin, quercetin, naringenin, and gallic acid by validated RP-and NP-HPTLC methods for quality control of anti-HBV active extract of Guiera …

P Alam, MK Parvez, AH Arbab… - Pharmaceutical …, 2017 - Taylor & Francis
Abstract Context: Guiera senegalensis JF Gmel (Combretaceae) is a folk medicinal plant
used in various metabolic and infectious diseases. In addition to its antiviral activities against …

Assessment of protective potential of Nigella sativa oil against carbendazim- and/or mancozeb-induced hematotoxicity, hepatotoxicity, and genotoxicity

MA Hashem, WAM Mohamed, ESM Attia - Environmental Science and …, 2018 - Springer
Nigella sativa oil (NSO) possesses antioxidant activity. However, its protective role against
the hazards of fungicides has been poorly studied. Therefore, the present work aimed at …

Fibrates in the management of atherogenic dyslipidemia

B Okopień, L Buldak, A Bołdys - Expert review of cardiovascular …, 2017 - Taylor & Francis
Introduction: Significant advancements in the treatment of hypercholesterolemia have
recently been achieved. However, a considerable level of residual cardiovascular risk still …

Genome-protecting compounds as potential geroprotectors

E Proshkina, M Shaposhnikov, A Moskalev - International journal of …, 2020 - mdpi.com
Throughout life, organisms are exposed to various exogenous and endogenous factors that
cause DNA damages and somatic mutations provoking genomic instability. At a young age …