[HTML][HTML] Review of the isolation, characterization, biological function, and multifarious therapeutic approaches of exosomes

S Gurunathan, MH Kang, M Jeyaraj, M Qasim, JH Kim - Cells, 2019 - mdpi.com
Exosomes are extracellular vesicles that contain a specific composition of proteins, lipids,
RNA, and DNA. They are derived from endocytic membranes and can transfer signals to …

[HTML][HTML] Current knowledge on exosome biogenesis, cargo-sorting mechanism and therapeutic implications

S Xie, Q Zhang, L Jiang - Membranes, 2022 - mdpi.com
Extracellular vesicles (EVs) are nanoscale membrane vesicles released by donor cells that
can be taken up by recipient cells. The study of EVs has the potential to identify unknown …

[HTML][HTML] Circulating microRNAs in cancer: potential and challenge

M Cui, H Wang, X Yao, D Zhang, Y Xie, R Cui… - Frontiers in …, 2019 - frontiersin.org
MicroRNAs (miRNAs) are endogenous non-coding small RNA molecules that can be
secreted into the circulation and exist in remarkably stable forms. Like intercellular miRNAs …

[HTML][HTML] miRNAs in cancer (review of literature)

B Smolarz, A Durczyński, H Romanowicz… - International journal of …, 2022 - mdpi.com
MicroRNAs (miRNAs) are short, noncoding, single-stranded RNA molecules that regulate
gene expression at the post-transcriptional level by binding to mRNAs. miRNAs affect the …

Exosome and exosomal microRNA: trafficking, sorting, and function

J Zhang, S Li, L Li, M Li, C Guo, J Yao… - Genomics, Proteomics …, 2015 - academic.oup.com
Abstract Exosomes are 40–100 nm nano-sized vesicles that are released from many cell
types into the extracellular space. Such vesicles are widely distributed in various body fluids …

Tumor-derived exosomes and their role in cancer progression

TL Whiteside - Advances in clinical chemistry, 2016 - Elsevier
Tumor cells actively produce, release, and utilize exosomes to promote tumor growth.
Mechanisms through which tumor-derived exosomes subserve the tumor are under intense …

Clinical relevance of circulating cell-free microRNAs in cancer

H Schwarzenbach, N Nishida, GA Calin… - Nature reviews Clinical …, 2014 - nature.com
Efficient patient management relies on early diagnosis of disease and monitoring of
treatment. In this regard, much effort has been made to find informative, blood-based …

Exosomes: novel biomarkers for clinical diagnosis

J Lin, J Li, B Huang, J Liu, X Chen… - The scientific world …, 2015 - Wiley Online Library
Exosomes are 30–120 nm endocytic membrane‐derived vesicles that participate in cell‐to‐
cell communication and protein and RNA delivery. Exosomes harbor a variety of proteins …

[HTML][HTML] Mesenchymal stem/stromal cell-derived exosomes in regenerative medicine and cancer; overview of development, challenges, and opportunities

A Hassanzadeh, HS Rahman, A Markov… - Stem cell research & …, 2021 - Springer
Recently, mesenchymal stem/stromal cells (MSCs) and their widespread biomedical
applications have attracted great consideration from the scientific community around the …

[HTML][HTML] Let-7 as biomarker, prognostic indicator, and therapy for precision medicine in cancer

E Chirshev, KC Oberg, YJ Ioffe… - Clinical and translational …, 2019 - Springer
Abnormal regulation and expression of microRNAs (miRNAs) has been documented in
various diseases including cancer. The miRNA let-7 (MIRLET7) family controls …