Altered neuronal and circuit excitability in fragile X syndrome

A Contractor, VA Klyachko, C Portera-Cailliau - Neuron, 2015 - cell.com
Fragile X syndrome (FXS) results from a genetic mutation in a single gene yet produces a
phenotypically complex disorder with a range of neurological and psychiatric problems …

Developmental studies in fragile X syndrome

KA Razak, KC Dominick, CA Erickson - Journal of neurodevelopmental …, 2020 - Springer
Fragile X syndrome (FXS) is the most common single gene cause of autism and intellectual
disabilities. Humans with FXS exhibit increased anxiety, sensory hypersensitivity, seizures …

[图书][B] Rethinking autism: Variation and complexity

LH Waterhouse, L Waterhouse - 2012 - books.google.com
The media, scientific researchers, and the Diagnostic and Statistical Manual all refer to"
autism" as if it were a single disorder or a single disorder over a spectrum. However, autism …

A comparison of FreeSurfer-generated data with and without manual intervention

CS McCarthy, A Ramprashad, C Thompson… - Frontiers in …, 2015 - frontiersin.org
This paper examined whether FreeSurfer—generated data differed between a fully—
automated, unedited pipeline and an edited pipeline that included the application of control …

Outcome measures for clinical trials in fragile X syndrome

E Berry-Kravis, D Hessl, L Abbeduto… - … of Developmental & …, 2013 - journals.lww.com
Objective: Progress in basic neuroscience has led to identification of molecular targets for
treatment in fragile X syndrome (FXS) and other neurodevelopmental disorders; however …

Neurodevelopmental origin of cognitive impairment in schizophrenia

E Bora - Psychological medicine, 2015 - cambridge.org
Cognitive impairment is a common feature of schizophrenia; however, its origin remains
controversial. Neurodevelopmental abnormalities clearly play a role in pre-morbid cognitive …

Post-error recruitment of frontal sensory cortical projections promotes attention in mice

KJ Norman, JS Riceberg, H Koike, J Bateh… - Neuron, 2021 - cell.com
The frontal cortex, especially the anterior cingulate cortex area (ACA), is essential for
exerting cognitive control after errors, but the mechanisms that enable modulation of …

Public health literature review of fragile X syndrome

M Raspa, AC Wheeler, C Riley - Pediatrics, 2017 - publications.aap.org
OBJECTIVES: The purpose of this systematic literature review is to describe what is known
about fragile X syndrome (FXS) and to identify research gaps. The results can be used to …

[HTML][HTML] Functional network integration and attention skills in young children

CS Rohr, A Arora, IYK Cho, P Katlariwala… - Developmental cognitive …, 2018 - Elsevier
Children acquire attention skills rapidly during early childhood as their brains undergo vast
neural development. Attention is well studied in the adult brain, yet due to the challenges …

Auditory processing in fragile x syndrome

SE Rotschafer, KA Razak - Frontiers in cellular neuroscience, 2014 - frontiersin.org
Fragile X syndrome (FXS) is an inherited form of intellectual disability and autism. Among
other symptoms, FXS patients demonstrate abnormalities in sensory processing and …