Biogenesis of extracellular vesicles in protozoan parasites: The ESCRT complex in the trafficking fast lane?

A Cruz Camacho, D Alfandari, E Kozela… - PLoS …, 2023 - journals.plos.org
Extracellular vesicles (EVs) provide a central mechanism of cell–cell communication. While
EVs are found in most organisms, their pathogenesis-promoting roles in parasites are of …

Molecular interplays of the Entamoeba histolytica endosomal sorting complexes required for transport during phagocytosis

C Bañuelos, A Betanzos, R Javier-Reyna… - Frontiers in Cellular …, 2022 - frontiersin.org
Entamoeba histolytica, the causative agent of human amoebiasis, exhibits a continuous
membrane remodelling to exert its virulence properties. During this dynamic process, the …

[HTML][HTML] Entamoeba histolytica: EhADH, an Alix Protein, Participates in Several Virulence Events through Its Different Domains

D Zanatta, A Betanzos, E Azuara-Liceaga… - International Journal of …, 2024 - mdpi.com
Entamoeba histolytica is the protozoan causative of human amoebiasis. The EhADH
adhesin (687 aa) is a protein involved in tissue invasion, phagocytosis and host-cell lysis …

EhVps35, a retromer component, is a key factor in secretion, motility, and tissue invasion by Entamoeba histolytica

J Díaz-Valdez, R Javier-Reyna, A Galindo… - Frontiers in Cellular …, 2024 - frontiersin.org
In humans and Drosophila melanogaster, the functional convergence of the endosomal
sorting complex required for transport (ESCRT) machinery that is in charge of selecting …

EhVps23, an ESCRT-I Member, Is a Key Factor in Secretion, Motility, Phagocytosis and Tissue Invasion by Entamoeba histolytica

A Galindo, R Javier-Reyna, G García-Rivera… - Frontiers in Cellular …, 2022 - frontiersin.org
The EhVps23 protein, an orthologue of the yeast Vps23 and the mammalian TSG101
proteins, is the single member of the ESCRT-I complex of Entamoeba histolytica identified …

EhVps35, a retromer component, is involved in the recycling of the EhADH and Gal/GalNac virulent proteins of Entamoeba histolytica

J Díaz-Valdez, R Javier-Reyna, S Montaño… - Frontiers in …, 2024 - frontiersin.org
The retromer is a highly conserved eukaryotic complex formed by the cargo selective
complex (CSC) and the sorting nexin (SNX) dimer subcomplexes. Its function is protein …

Dynamic Association of ESCRT-II Proteins with ESCRT-I and ESCRT-III Complexes during Phagocytosis of Entamoeba histolytica

M Díaz-Hernández, R Javier-Reyna… - International Journal of …, 2023 - mdpi.com
By their active movement and voraux phagocytosis, the trophozoites of Entamoeba
histolytica constitute an excellent system to investigate the dynamics of the Endosomal …

Glutamic acid-lysine (EK) rich motif of RabD2 self-associates and regulates pathogenesis through multivesicular bodies pathway in E. histolytica

P Navyaka, K Verma - bioRxiv, 2024 - biorxiv.org
Entamoeba histolytica, an enteric pathogen, causes disease by adhering to and destroying
the host tissues. The interactions between the parasite and host tissue enable rewiring of the …

[HTML][HTML] Updates in molecules associated with pathogenesis of amoebiasis: A mini review

D Sharma, U Kaur, R Sehgal - South Asian Journal of Health …, 2023 - sajhealthsci.com
Amoebiasis caused due to the protozoan parasite Entamoeba histolytica has been ranked
as the third major reason of mortality after Malaria and Schistosomiasis. The pathogen …

[PDF][PDF] Caracterización funcional de los dominios de EhADH de Entamoeba histolytica

Z García, D Yolanda - 2024 - repositorio.cinvestav.mx
Entamoeba histolytica es el protozoo causante de la amibiasis humana. La adhesina
EhADH (687 aa) es una proteína implicada en la invasión de tejidos, la fagocitosis y la lisis …