Reductions in blood flow to the brain of sufficient duration and extent lead to stroke, which
results in damage to neuronal networks and the impairment of sensation, movement or …

Stroke remains a leading cause of adult disability. Some degree of spontaneous behavioral
recovery is usually seen in the weeks after stroke onset. Variability in recovery is substantial …

Adult mammalian brains have largely lost neuroregeneration capability except for a few
niches. Previous studies have converted glial cells into neurons, but the total number of …

Mesenchymal stem cells or multipotent stromal cells (MSCs) have initially captured attention
in the scientific world because of their differentiation potential into osteoblasts …

Enhancing the Alignment of the Preclinical and Clinical Stroke Recovery Research Pipeline:
Consensus-Based Core Recommendations From the Stroke Recovery and Rehabilitation …

One of the exciting advances in modern medicine and life science is cell-based
neurovascular regeneration of damaged brain tissues and repair of neuronal structures. The …

Spontaneous behavioral recovery is usually limited after stroke, making stroke a leading
source of disability. A number of therapies in development aim to improve patient outcomes …

Cerebral small vessel disease (SVD) is a major cause of stroke and dementia.
Pathologically, three lesions are seen: small vessel arteriopathy, lacunar infarction, and …

Background. Enriched rehabilitation (ER; environmental enrichment plus skilled reaching)
improves recovery after middle cerebral artery occlusion (MCAo) in rats. Fundamental …

Background. The proportional recovery rule suggests that current rehabilitation practices
may have limited ability to influence stroke recovery. However, the appropriate intensity of …