History, discovery, and classification of lncRNAs
J Jarroux, A Morillon, M Pinskaya - Long non coding RNA biology, 2017 - Springer
Abstract The RNA World Hypothesis suggests that prebiotic life revolved around RNA
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
instead of DNA and proteins. Although modern cells have changed significantly in 4 billion …
Genetics of primary ovarian insufficiency: new developments and opportunities
Y Qin, X Jiao, JL Simpson… - Human reproduction …, 2015 - academic.oup.com
BACKGROUND Primary ovarian insufficiency (POI) is characterized by marked
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …
heterogeneity, but with a significant genetic contribution. Identifying exact causative genes …
ReMap 2022: a database of Human, Mouse, Drosophila and Arabidopsis regulatory regions from an integrative analysis of DNA-binding sequencing experiments
F Hammal, P De Langen, A Bergon… - Nucleic acids …, 2022 - academic.oup.com
Abstract ReMap (https://remap. univ-amu. fr) aims to provide manually curated, high-quality
catalogs of regulatory regions resulting from a large-scale integrative analysis of DNA …
catalogs of regulatory regions resulting from a large-scale integrative analysis of DNA …
DNABERT: pre-trained Bidirectional Encoder Representations from Transformers model for DNA-language in genome
Motivation Deciphering the language of non-coding DNA is one of the fundamental
problems in genome research. Gene regulatory code is highly complex due to the existence …
problems in genome research. Gene regulatory code is highly complex due to the existence …
Dnabert-2: Efficient foundation model and benchmark for multi-species genome
Decoding the linguistic intricacies of the genome is a crucial problem in biology, and pre-
trained foundational models such as DNABERT and Nucleotide Transformer have made …
trained foundational models such as DNABERT and Nucleotide Transformer have made …
Cistrome and epicistrome features shape the regulatory DNA landscape
The cistrome is the complete set of transcription factor (TF) binding sites (cis-elements) in an
organism, while an epicistrome incorporates tissue-specific DNA chemical modifications and …
organism, while an epicistrome incorporates tissue-specific DNA chemical modifications and …
Phased diploid genome assembly with single-molecule real-time sequencing
While genome assembly projects have been successful in many haploid and inbred
species, the assembly of noninbred or rearranged heterozygous genomes remains a major …
species, the assembly of noninbred or rearranged heterozygous genomes remains a major …
Cell-cycle dynamics of chromosomal organization at single-cell resolution
Chromosomes in proliferating metazoan cells undergo marked structural metamorphoses
every cell cycle, alternating between highly condensed mitotic structures that facilitate …
every cell cycle, alternating between highly condensed mitotic structures that facilitate …
Functional annotations of three domestic animal genomes provide vital resources for comparative and agricultural research
Gene regulatory elements are central drivers of phenotypic variation and thus of critical
importance towards understanding the genetics of complex traits. The Functional Annotation …
importance towards understanding the genetics of complex traits. The Functional Annotation …
Epigenomic signatures of neuronal diversity in the mammalian brain
Neuronal diversity is essential for mammalian brain function but poses a challenge to
molecular profiling. To address the need for tools that facilitate cell-type-specific epigenomic …
molecular profiling. To address the need for tools that facilitate cell-type-specific epigenomic …